Evidence map›Paper›PMID 24987451›Full record

ArticleComputational and mathematical methods in medicine2014

Automatic lung tumor segmentation on PET/CT images using fuzzy Markov random field model.

Yu Guo, Yuanming Feng, Jian Sun, Ning Zhang, Wang Lin, Yu Sa, Ping Wang

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Article in Computational and mathematical methods in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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5 citing papers in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Yu GuoTianjin Key Lab of BME Measurement, Tianjin University, Tianjin 300072, China.
Yuanming FengTianjin Key Lab of BME Measurement, Tianjin University, Tianjin 300072, China ; Department of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
Jian SunDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
Ning ZhangTianjin Key Lab of BME Measurement, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-1559-111X
Wang LinTianjin Key Lab of BME Measurement, Tianjin University, Tianjin 300072, China.
Yu SaTianjin Key Lab of BME Measurement, Tianjin University, Tianjin 300072, China.
Ping WangDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of positron emission tomography (PET) and CT images provides complementary functional and anatomical information of human tissues and it has been used for better tumor volume definition of lung cancer. This paper proposed a robust method for automatic lung tumor segmentation on PET/CT images. The new method is based on fuzzy Markov random field (MRF) model. The combination of PET and CT image information is achieved by using a proper joint posterior probability distribution of observed features in the fuzzy MRF model which performs better than the commonly used Gaussian joint distribution. In this study, the PET and CT simulation images of 7 non-small cell lung cancer (NSCLC) patients were used to evaluate the proposed method. Tumor segmentations with the proposed method and manual method by an experienced radiation oncologist on the fused images were performed, respectively. Segmentation results obtained with the two methods were similar and Dice's similarity coefficient (DSC) was 0.85 ± 0.013. It has been shown that effective and automatic segmentations can be achieved with this method for lung tumors which locate near other organs with similar intensities in PET and CT images, such as when the tumors extend into chest wall or mediastinum.

Indexed as

AlgorithmsCarcinoma, Non-Small-Cell LungCell Line, TumorFuzzy LogicHumansLung NeoplasmsMarkov ChainsModels, StatisticalMultimodal ImagingPattern Recognition, AutomatedPositron-Emission TomographyProbabilityRadiographic Image Interpretation, Computer-AssistedSoftwareTomography, X-Ray Computed

Identifiers

PMID24987451
PMCPMC4058834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.