ArticleThe journal of venomous animals and toxins including tropical diseases2014
Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report.
Article in The journal of venomous animals and toxins including tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Snakebite associated thrombotic microangiopathy: a systematic review of clinical features, outcomes, and evidence for interventions including plasmapheresis.PLoS neglected tropical diseases · 2020Pooled it
- Platelet Desialylation Is a Novel Mechanism and Therapeutic Target inMolecules (Basel, Switzerland) · 2022Article
- Snakebite Associated Thrombotic Microangiopathy and Recommendations for Clinical Practice.Toxins · 2022Review
- Article
- Evolutionary Interpretations of Nicotinic Acetylcholine Receptor Targeting Venom Effects by a Clade of Asian Viperidae Snakes.Neurotoxicity research · 2020Article
- Snakebite associated thrombotic microangiopathy: a protocol for the systematic review of clinical features, outcomes, and role of interventions.Systematic reviews · 2019Article
- An Atypical Clinical Manifestation of a Hump-Nosed Pit Viper Envenomation.Case reports in medicine · 2019Article
- Thrombocytopenic purpura following envenomation by the nose-horned viper (Vipera ammodytes ammodytes): Two case reports.Medicine · 2018Article
- Acute myocardial infarction associated with thrombotic microangiopathy following a hump-nosed viper bite: a case report.Journal of medical case reports · 2017Article
- Snakebite Induced Thrombotic Microangiopathy Leading to Renal Cortical Necrosis.Case reports in nephrology · 2017Article
- Thrombotic Microangiopathy: An Under-Recognised Cause of Snake-bite-related Acute Kidney Injury.Indian journal of nephrologyArticle
- Thrombotic microangiopathy due toIndian journal of nephrologyArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hump-nosed viper bites are frequent in southern India and Sri Lanka. However, the published literature on this snakebite is limited and its venom composition is not well characterized. In this case, we report a patient with thrombotic thrombocytopenic purpura-like syndrome following envenoming which, to the best of our knowledge, has not been reported in the literature before. A 55-year-old woman from southern Sri Lanka presented to the local hospital 12 hours after a hump-nosed viper (Hypnale hypnale) bite. Five days later, she developed a syndrome that was characteristic of thrombotic thrombocytopenic purpura with fever, thrombocytopenia, microangiopathic hemolysis, renal impairment and neurological dysfunction in the form of confusion and coma. Her clinical syndrome and relevant laboratory parameters improved after she was treated with therapeutic plasma exchange. We compared our observations on this patient with the current literature and concluded that thrombotic thrombocytopenic purpura is a theoretically plausible yet unreported manifestation of hump-nosed viper bite up to this moment. This study also provides an important message for clinicians to look out for this complication in hump-nosed viper bites since timely treatment can be lifesaving.
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