Evidence map›Paper›PMID 24986852›Full record

ArticleThe Journal of rheumatology2014

Longterm blood pressure variability in patients with rheumatoid arthritis and its effect on cardiovascular events and all-cause mortality in RA: a population-based comparative cohort study.

Elena Myasoedova, Cynthia S Crowson, Abigail B Green, Eric L Matteson, Sherine E Gabriel

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The Journal of rheumatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Observational
  5. Article
  6. Short-Term Variability of Both Brachial and Aortic Blood Pressure is Increased in Patients with Immune-mediated Chronic Inflammation.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Article
  7. Commentary on "Short-Term Variability of Both Brachial and Aortic Blood Pressure is Increased in Patients with Immune-Mediated Chronic Inflammation".High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Article
  8. Article
  9. Frequency and Predictors of Communication About High Blood Pressure in Rheumatoid Arthritis Visits.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elena MyasoedovaFrom the Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.E. Myasoedova, MD, PhD; C.S. Crowson, MS, Department of Health Sciences Research, and the Division of Rheumatology; A.B. Green, MS, Department of Health Sciences Research; E.L. Matteson, MD, MPH; S.E. Gabriel, MD, MSc, Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine.
Cynthia S CrowsonFrom the Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.E. Myasoedova, MD, PhD; C.S. Crowson, MS, Department of Health Sciences Research, and the Division of Rheumatology; A.B. Green, MS, Department of Health Sciences Research; E.L. Matteson, MD, MPH; S.E. Gabriel, MD, MSc, Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine. crowson@mayo.edu.
Abigail B GreenFrom the Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.E. Myasoedova, MD, PhD; C.S. Crowson, MS, Department of Health Sciences Research, and the Division of Rheumatology; A.B. Green, MS, Department of Health Sciences Research; E.L. Matteson, MD, MPH; S.E. Gabriel, MD, MSc, Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine.
Eric L MattesonFrom the Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.E. Myasoedova, MD, PhD; C.S. Crowson, MS, Department of Health Sciences Research, and the Division of Rheumatology; A.B. Green, MS, Department of Health Sciences Research; E.L. Matteson, MD, MPH; S.E. Gabriel, MD, MSc, Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine.
Sherine E GabrielFrom the Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.E. Myasoedova, MD, PhD; C.S. Crowson, MS, Department of Health Sciences Research, and the Division of Rheumatology; A.B. Green, MS, Department of Health Sciences Research; E.L. Matteson, MD, MPH; S.E. Gabriel, MD, MSc, Department of Health Sciences Research, and the Division of Rheumatology, Mayo Clinic College of Medicine.
Center for Rheumatology · USGreen Cross International · US

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
HEART DISEASE IN RHEUMATOID ARTHRITISR01AR046849 · NIAMS · MAYO CLINIC ROCHESTER · PI CROWSON, CYNTHIA S · 2000 to 2022
$11.3M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
NCATS NIH HHS UL1 TR000135NIAMS NIH HHS R01 AR046849NIAMS NIH HHS R01 AR46849NIA NIH HHS R01 AG034676NIA NIH HHS R01AG034676
6 · The paper itself

Abstract

objectiveTo examine longterm visit-to-visit blood pressure (BP) variability in patients with rheumatoid arthritis (RA) versus non-RA subjects and to assess its effect on cardiovascular (CV) events and mortality in RA.

methodsClinic BP measures were collected in a population-based incident cohort of patients with RA (1987 American College of Rheumatology criteria met between January 1, 1995, and January 1, 2008) and non-RA subjects. BP variability was defined as within-subject SD in systolic and diastolic BP.

resultsThe study included 442 patients with RA (mean age 55.5 yrs, 70% females) and 424 non-RA subjects (mean age 55.7 yrs, 69% females). Patients with RA had higher visit-to-visit variability in systolic BP (13.8 ± 4.7 mm Hg) than did non-RA subjects (13.0 ± 5.2 mm Hg, p = 0.004). Systolic BP variability declined after the index date in RA (p < 0.001) but not in the non-RA cohort (p = 0.73), adjusting for age, sex, and calendar year of RA. During the mean followup of 7.1 years, 33 CV events and 57 deaths occurred in the RA cohort. Visit-to-visit systolic BP variability was associated with increased risk of CV events (HR per 1 mm Hg increase in BP variability 1.12, 95% CI 1.01-1.25). Diastolic BP variability was associated with all-cause mortality in RA (HR 1.14, 95% CI 1.03-1.27), adjusting for systolic and diastolic BP, body mass index, smoking, diabetes, dyslipidemia, and use of antihypertensives.

conclusionPatients with RA had higher visit-to-visit systolic BP variability than did non-RA subjects. There was a significant decline in systolic BP variability after RA incidence. Higher visit-to-visit BP variability was associated with adverse CV outcomes and all-cause mortality in RA.

Indexed as

AdultAgedAntihypertensive AgentsAntirheumatic AgentsArthritis, RheumatoidBlood PressureCardiovascular DiseasesCohort StudiesFemaleHumansHypertensionIncidenceLongitudinal StudiesMaleMiddle AgedOffice VisitsAntihypertensive AgentsAntirheumatic AgentsBLOOD PRESSURE VARIABILITYRHEUMATOID ARTHRITISTRENDS

Identifiers

PMID24986852
PMCPMC4159667
OpenAlexW1997427009

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.