Evidence map›Paper›PMID 24986772›Full record

ReviewExpert opinion on drug delivery2014

The potential of magneto-electric nanocarriers for drug delivery.

Ajeet Kaushik, Rahul Dev Jayant, Vidya Sagar, Madhavan Nair

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on drug delivery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 109 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Nanoparticle-based Gene Therapy for Neurodegenerative Disorders.Mini reviews in medicinal chemistry · 2024
    Review
  7. Alzheimer's Disease: Treatment Strategies and Their Limitations.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
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  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ajeet KaushikFlorida International University, Institute of Neuroimmune Pharmacology, Herbert Wertheim College of Medicine, Center of Personalized Nanomedicine, Department of Immunology , Miami, FL-33199 , USA.
Rahul Dev Jayant
Vidya Sagar
Madhavan Nair
Florida International University · US

Funding

Polydrug Nanocarrier to Treat Opiate Addiction and HIV DiseaseR01DA027049 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2009 to 2014
$3.1M
Cocaine in the Neuropathogenesis of HIV infection: Role of HDAC2R01DA034547 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2013 to 2018
$1.8M
Mechanisms of Neuro-AIDS by HIV 1B and C CladesR01MH085259 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2010 to 2014
$1.7M
Novel Magneto-Electric Nanodelivery of Drugs to Eradicate HIV from CNSR21MH101025 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2013 to 2014
$388k
NIDA NIH HHS 1R01-DA027049NIDA NIH HHS R01 DA027049NIDA NIH HHS R01 DA 034547.NIDA NIH HHS R01 DA034547NIMH NIH HHS R01 MH085259NIMH NIH HHS R21 MH 101025NIMH NIH HHS R21 MH101025
6 · The paper itself

Abstract

introductionThe development and design of personalized nanomedicine for better health quality is receiving great attention. In order to deliver and release a therapeutic concentration at the target site, novel nanocarriers (NCs) were designed, for example, magneto-electric (ME) which possess ideal properties of high drug loading, site-specificity and precise on-demand controlled drug delivery. AREAS COVERED: This review explores the potential of ME-NCs for on-demand and site-specific drug delivery and release for personalized therapeutics. The main features including effect of magnetism, improvement in drug loading, drug transport across blood-brain barriers and on-demand controlled release are also discussed. The future directions and possible impacts on upcoming nanomedicine are highlighted. EXPERT OPINION: Numerous reports suggest that there is an urgent need to explore novel NC formulations for safe and targeted drug delivery and release at specific disease sites. The challenges of formulation lie in the development of NCs that improve biocompatibility and surface modifications for optimum drug loading/preservation/transmigration and tailoring of electrical-magnetic properties for on-demand drug release. Thus, the development of novel NCs is anticipated to overcome the problems of targeted delivery of therapeutic agents with desired precision that may lead to better patient compliance.

Indexed as

Drug CarriersDrug Delivery SystemsElectromagnetic PhenomenaAnimalsBlood-Brain BarrierChemistry, PharmaceuticalHumansNanoparticlesPharmaceutical PreparationsDrug CarriersPharmaceutical Preparationsdrug deliverymagneto-electric nanocarriersnanocarrierstherapeutic agent

Identifiers

PMID24986772
PMCPMC4556109
OpenAlexW1968861900

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.