ReviewCurrent osteoporosis reports2014
Underweight, overweight, and pediatric bone fragility: impact and management.
Review in Current osteoporosis reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00310791 (Effects of Adrenal and Gonadal Hormone Replacement in Young Women With Anorexia Nervosa), which is not on this map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Adrenal and Gonadal Hormone Replacement in Young Women With Anorexia Nervosa
Who cites it
25 citing papers in PubMed, 53 citations in OpenAlex.
- Bone health in juvenile idiopathic arthritis compared with controls based on a Norwegian observational study.RMD open · 2025Trial
- Comparison of body composition between thin and normal-weight sarcopenic children: a single-center, propensity score matching analysis of a large-scale study.BMC pediatrics · 2026Article
- SOCCERSports (Basel, Switzerland) · 2026Article
- Adolescents with Low Body Mass Index Are More Vulnerable to Pediatric Nondisplaced Femoral Neck Fractures.Clinics in orthopedic surgery · 2025Article
- Effect of early tooth eruption on the development of dental caries in children: a cross-sectional study.BMC oral health · 2025Article
- The "Burden" of Childhood Obesity on Bone Health: A Look at Prevention and Treatment.Nutrients · 2025Review
- Understanding Bone Density Loss in Eating Disorders: Contributions of Weight Suppression and Speed of Weight Loss.Journal of clinical medicine · 2024Article
- Is underweight associated with poorer diet, nutrient status, bone and cardiometabolic health, and school performance in Danish 8-11-year-olds?European journal of nutrition · 2024Article
- Bone health in childhood low-grade glioma: an understudied problem.Endocrine connections · 2024Article
- The role of bone health in low-velocity fractures and the effects of obesity on the growing skeleton.Journal of the Pediatric Orthopaedic Society of North America · 2024Article
- Age- and height-dependent bias of underweight and overweight assessment standards for children and adolescents.Frontiers in public health · 2024Article
- Evaluation of bone mineral density and bone turnover in children on anticoagulation.Frontiers in endocrinology · 2023Article
- L'évaluation et l'optimisation de la santé osseuse chez les enfants ayant des affections chroniques.Paediatrics & child health · 2022Article
- Evaluating and optimizing bone health in children with chronic health conditions.Paediatrics & child health · 2022Article
- Determinants of Bone Mineral Density in Transgender Youth.Transgender health · 2022Article
- Nutritional status and associated factors of older persons in sub-Saharan Africa: a scoping review.BMC geriatrics · 2022Article
- The relationship between extremity fractures and visual impairment in childhood: A case-control study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Consumption of Cow's Milk in Early Childhood and Fracture Risk: A Prospective Cohort Study.American journal of epidemiology · 2020Article
- Reply to Letter to the Editor: Regarding "The Role of Obesity in Pediatric Orthopedics".Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2020Article
- Letter to the Editor: Regarding "The Role of Obesity in Pediatric Orthopedics".Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Skeletal health is modulated by a variety of factors, including genetic makeup, hormonal axes, and environment. Across all ages, extremes of body weight may exert a deleterious effect on bone accretion and increase fracture risk. The incidence of both anorexia nervosa and obesity, each involving extreme alterations in body composition, is rising among youth, and secondary osteoporosis is increasingly being diagnosed among affected children and adolescents. Compared with the elderly, the definition of osteoporosis that stems from any underlying condition differs for the pediatric population and special precautions are required with regard to treatment of young patients. Early recognition and management of both underweight and overweight youth and the accompanying consequences on bone and mineral metabolism are essential for preservation of skeletal health, although prevention of bone loss and optimization of bone mineral accrual remain the most important protective measures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.