SynthesisHeart failure reviews2014
BNP and NT-proBNP as prognostic markers in persons with chronic stable heart failure.
Synthesis in Heart failure reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.
- Prognostic Value of Natriuretic Peptides for All-Cause Mortality, Right Ventricular Failure, Major Adverse Events, and Myocardial Recovery in Advanced Heart Failure Patients Receiving a Left Ventricular Assist Device: A Systematic Review.Frontiers in cardiovascular medicine · 2021Pooled it
- Thyroid feedback quantile-based index predicts 90-day all-cause mortality or readmission in hospitalized heart failure patients: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Effectiveness of sarcopenia screening indicators in predicting death in older patients with chronic heart failure.BMC geriatrics · 2025Article
- Comparison of Natriuretic Peptide Levels in Sinus Rhythm and Atrial Fibrillation in Acute Heart Failure.International journal of heart failure · 2025Article
- Proposed Novel Heart Failure Biomarkers and Their Association with Length of Hospital Stay and Mortality: A Retrospective Observational Pilot Study.Diagnostics (Basel, Switzerland) · 2025Article
- Short sleep duration in adults with congenital heart disease is associated with epicardial adipose tissue accumulation.Frontiers in psychiatry · 2025Article
- Prognostic relevance of global work index and global constructive work in patients with non-ischemic dilated cardiomyopathy.The international journal of cardiovascular imaging · 2024Article
- Therapeutic effect of adipose-derived stem cells injected into pericardial cavity in rat heart failure.ESC heart failure · 2024Article
- Prognostic Value of Systemic Inflammation Response Index and N-Terminal Pro-B-Type Natriuretic Peptide in Patients with Myocardial Infarction with Nonobstructive Coronary Arteries- A Retrospective Study.Journal of inflammation research · 2024Article
- Association of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and acute kidney disease in patients undergoing coronary angiography: a cohort study.International urology and nephrology · 2023Article
- NT-proBNP as a surrogate for unknown heart failure and its predictive power for peripheral artery disease outcome and phenotype.Scientific reports · 2023Article
- sST2 and Heart Failure-Clinical Utility and Prognosis.Journal of clinical medicine · 2023Article
- Article
- Effectiveness of Spironolactone in Terms of Galectin-3 Levels in Patients with Heart Failure with a Reduced Ejection Fraction in the Vietnamese Population.Healthcare (Basel, Switzerland) · 2023Article
- The relationship between peripheral blood soluble ST2, BNP levels, cardiac function, and prognosis in patients with heart failure.American journal of translational research · 2023Article
- The Prognostic Value of B-Type Natriuretic Peptide in Patients With Cardiac Sarcoidosis Without Heart Failure: Insights From ILLUMINATE-CS.Journal of the American Heart Association · 2022Observational
- Neutrophilic granulocyte percentage is associated with anxiety in Chinese hospitalized heart failure patients.BMC cardiovascular disorders · 2022Article
- Endocrine hormone imbalance in heart failure with reduced ejection fraction: A cross-sectional study.Health science reports · 2022Article
- Insulin-like growth factor-1 (IGF-1) as predictor of cardiovascular mortality in heart failure patients: data from the T.O.S.CA. registry.Internal and emergency medicine · 2022Article
- Positive relationships between annual changes in salt intake and plasma B-type natriuretic peptide levels in the general population without hypertension and heart diseases.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prognosis permits clinicians to separate persons with heart failure (HF) into subgroups based on likely health outcomes. Treatment is partly guided by these likely outcomes. This systematic review explores whether brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) are independent predictors of prognosis in persons with chronic stable HF. We electronically searched Medline, Embase, AMED, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and CINAHL for English-language articles published between 1989 and mid-2012. We utilized trained reviewers and standardized forms to screen articles for inclusion and extracted data from included articles. All included studies were summarized in narrative and tabular form. We used the Hayden criteria to assess the risk of bias. Sixteen BNP publications and 88 NT-proBNP publications were included in the systematic review. BNP was positively associated with all-cause and HF mortality. NT-proBNP was positively associated with all-cause and cardiovascular mortality. BNP and NT-proBNP levels are useful for estimating prognosis in persons with chronic stable HF. Further research is required to establish optimal cutpoints and to assess whether prognostic effects differ by age, sex, or time period.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.