ArticleDevelopmental psychobiology2014
Neonatal amygdala lesions alter mother-infant interactions in rhesus monkeys living in a species-typical social environment.
Article in Developmental psychobiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 34 citations in OpenAlex.
- Social Status Shapes Maternal Style Toward Rhesus Macaque Infants in the First Year of Life.Developmental psychobiology · 2026Article
- Prenatal Zika virus exposure disrupts social-emotional development and cortical visual function in infant macaques.Nature communications · 2026Article
- Amygdala circuit transitions supporting developmentally-appropriate social behavior.Neurobiology of learning and memory · 2023Review
- Infant pain vs. pain with parental suppression: Immediate and enduring impact on brain, pain and affect.PloS one · 2023Article
- The Neurobiology of Infant Attachment-Trauma and Disruption of Parent-Infant Interactions.Frontiers in behavioral neuroscience · 2022Review
- Bidirectional control of infant rat social behavior via dopaminergic innervation of the basolateral amygdala.Neuron · 2021Article
- Astrogliosis in juvenile non-human primates 2 years after infant anaesthesia exposure.British journal of anaesthesia · 2021Article
- Neurobiology of Infant Fear and Anxiety: Impacts of Delayed Amygdala Development and Attachment Figure Quality.Biological psychiatry · 2021Review
- Neuregulins in Neurodegenerative Diseases.Frontiers in aging neuroscience · 2021Article
- Validation of the Social Responsiveness Scale (SRS) to screen for atypical social behaviors in juvenile macaques.PloS one · 2021Article
- Social Regulation of Negative Valence Systems During Development.Frontiers in systems neuroscience · 2021Review
- Emotional responses in monkeys differ depending on the stimulus type, sex, and neonatal amygdala lesion status.Behavioral neuroscience · 2020Article
- Bridging the species gap in translational research for neurodevelopmental disorders.Neurobiology of learning and memory · 2019Article
- Advances in nonhuman primate models of autism: Integrating neuroscience and behavior.Experimental neurology · 2018Review
- Early life adversity during the infant sensitive period for attachment: Programming of behavioral neurobiology of threat processing and social behavior.Developmental cognitive neuroscience · 2017Review
- Blockade of glutamatergic transmission in the primate basolateral amygdala suppresses active behavior without altering social interaction.Behavioral neuroscience · 2017Article
- The effects of neonatal amygdala or hippocampus lesions on adult social behavior.Behavioural brain research · 2017Article
- Early amygdala or hippocampus damage influences adolescent female social behavior during group formation.Behavioral neuroscience · 2017Article
- Emergence of social behavior deficit, blunted corticolimbic activity and adult depression-like behavior in a rodent model of maternal maltreatment.Translational psychiatry · 2016Article
- Bidirectional Control of Social Behavior by Activity within Basolateral and Central Amygdala of Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The current study examined the effects of neonatal amygdala lesions on mother-infant interactions in rhesus monkeys reared in large species-typical social groups. Focal observations of mother-infant interactions were collected in their social group for the first 12 months postpartum on infants that had received amygdala lesions (Neo-A) at 24-25 days of age and control infants. Early amygdala lesions resulted in subtle behavioral alterations. Neo-A females exhibited earlier emergence of independence from the mother than did control females, spending more time away from their mother, whereas Neo-A males did not. Also, a set of behaviors, including coo vocalizations, time in contact, and time away from the mother, accurately discriminated Neo-A females from control females, but not Neo-A and control males. Data suggest that neonatal amygdalectomy either reduced fear, therefore increasing exploration in females, or reduced the positive reward value of maternal contact. Unlike females, neonatal amygdala lesions had little measurable effects on male mother-infant interactions. The source of this sex difference is unknown.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.