Evidence map›Paper›PMID 24986063›Full record

ReviewTrends in molecular medicine2014

Noncoding RNAs: key molecules in understanding and treating pain.

Kiran Kumar Bali, Rohini Kuner

Open access · bronzeAbstract readReview
In one paragraph

Review in Trends in molecular medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
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  9. Review
  10. Peripheral mechanisms of peripheral neuropathic pain.Frontiers in molecular neuroscience · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Genetics and Epigenetics of Spontaneous Intracerebral Hemorrhage.International journal of molecular sciences · 2022
    Review
  17. Review
  18. Article
  19. Review
  20. Review

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kiran Kumar BaliInstitute for Pharmacology, Im Neuenheimer Feld 366, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany; Molecular Medicine Partnership Unit with European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany. Electronic address: kiran.bali@pharma.uni-heidelberg.de.
Rohini KunerInstitute for Pharmacology, Im Neuenheimer Feld 366, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany; Molecular Medicine Partnership Unit with European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany. Electronic address: rohini.kuner@pharma.uni-heidelberg.de.
University Hospital Heidelberg · DE

Funding

European Research Council 294293Worldwide Cancer Research 10-0682
6 · The paper itself

Abstract

Although noncoding RNAs (ncRNAs) were initially considered to be transcriptional byproducts, recent technological advances have led to a steady increase in our understanding of their importance in gene regulation and disease pathogenesis. In keeping with these developments, pain research is also experiencing rapid growth in the investigation of links between ncRNAs and pathological pain. Although the initial focus was on analyzing expression and dysregulation of candidate miRNAs, elucidation of other ncRNAs and ncRNA-mediated functional mechanisms in pain modulation has just commenced. Here we review the major ncRNA literature available to date with respect to pain modulation and discuss tools and opportunities available for testing the impact of other types of ncRNA on pain.

Indexed as

AnimalsBrainGene Expression RegulationHumansPainPain ManagementRNA, UntranslatedSpinal CordRNA, Untranslatedchronic painlncRNAmiRNAncRNApain mechanisms

Identifiers

PMID24986063
PMCPMC4123187
OpenAlexW2019029520

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.