Evidence map›Paper›PMID 24985124›Full record

Trial reportEuropean journal of pediatrics2015

Successful management of an outbreak due to carbapenem-resistant Acinetobacter baumannii in a neonatal intensive care unit.

Olga Tsiatsiou, Εlias Iosifidis, Aspasia Katragkou, Vasiliki Dimou, Kosmas Sarafidis, Theodoros Karampatakis, Charalampos Antachopoulos, Anagnostina Orfanou, Athanasios Tsakris, Vasiliki Drossou-Agakidou and 1 more

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Molecular, biofilm and motility characterization ofFrontiers in cellular and infection microbiology · 2025
    Article
  3. Article
  4. Frontiers in antibiotics · 2024
    Review
  5. Article
  6. Article
  7. Control of Healthcare-Associated Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Control ofAntimicrobial resistance and infection control · 2019
    Article
  14. Acinetobacter Infections in Neonates.Current infectious disease reports · 2018
    Review
  15. Outbreaks in the neonatal ICU: a review of the literature.Current opinion in infectious diseases · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Olga TsiatsiouInfectious Diseases Unit, 3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration General Hospital, Konstantinoupoleos 49, 546 42, Thessaloniki, Greece, olgatsi@otenet.gr.
Εlias Iosifidis
Aspasia Katragkou
Vasiliki Dimou
Kosmas Sarafidis
Theodoros Karampatakis
Charalampos Antachopoulos
Anagnostina Orfanou
Athanasios Tsakris
Vasiliki Drossou-Agakidou
Emmanuel Roilides
Hippocration General Hospital · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledThe investigation and successful management of a monoclonal Acinetobacter baumannii outbreak in a neonatal intensive care unit are described. Upon the first clustered carbapenem-resistant A. baumannii (CRAB) infections, a bundle of actions were taken, including enhanced infection control, active surveillance (weekly stool samples), case-control study, staff education, daily audits and discontinuation of new admissions. Between September and December 2011, eight neonates developed 10 CRAB infections (five blood, four respiratory and one eye). A total of 216 active surveillance cultures were obtained from 96 neonates (43 % had ≥2 samples). During weeks 12, 16 and 17, active surveillance detected 3, 1 and 2 new CRAB acquisitions, respectively. Prevalence of infections/colonizations decreased, and no event occurred after 20th week. A colonized neonate developed CRAB sepsis and died. All CRAB isolates harboured bla OXA-58 and the intrinsic chromosomal bla OXA-51 carbapenemase genes.

conclusionActive surveillance and enhanced infection control measures effectively contained spread of CRAB clone in the neonatal intensive care unit.

Indexed as

beta-Lactam ResistanceDisease OutbreaksAcinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial Agentsbeta-LactamasesCarbapenemsColistinFecesHumansInfant, NewbornIntensive Care Units, NeonatalMeropenemProspective StudiesThienamycinsAnti-Bacterial Agentsbeta-lactamase OXA-51, Acinetobacter baumanniibeta-lactamase OXA-58, Acinetobacter baumanniibeta-LactamasesCarbapenemsColistinMeropenemThienamycins

Identifiers

PMID24985124
OpenAlexW1994249256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.