ArticleFolia microbiologica2015
Biofilm formation by Staphylococcus hominis strains isolated from human clinical specimens.
Article in Folia microbiologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- Heterogeneity of Biofilm Formation AmongAntibiotics (Basel, Switzerland) · 2025Article
- Sticking together: independent evolution of biofilm formation in different species of staphylococci has occurred multiple times via different pathways.BMC genomics · 2024Article
- Antibiofilm activity of Cutibacterium acnes cell-free conditioned media against Staphylococcus spp.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- A Journey on the Skin Microbiome: Pitfalls and Opportunities.International journal of molecular sciences · 2021Review
- Antimicrobial and Antibiofilm Activity of the Probiotic StrainAntibiotics (Basel, Switzerland) · 2021Article
- The staphylococcal exopolysaccharide PIA - Biosynthesis and role in biofilm formation, colonization, and infection.Computational and structural biotechnology journal · 2020Review
- Article
- Safety Evaluation of Individual Pillboxes to Control Cross-Contamination in the Drug Circuit in Hospitals.International journal of environmental research and public health · 2019Article
- Non-biofilm-forming commensal Staphylococcus epidermidis isolates produce biofilm in the presence of trypsin.MicrobiologyOpen · 2019Article
- Comparison of the etiological relevance of Staphylococcus haemolyticus and Staphylococcus hominis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Article
- Multifactorial mechanisms of the pathogenesis of methicillin-resistant Staphylococcus hominis isolated from bloodstream infections.Antonie van Leeuwenhoek · 2018Article
- Molecular basis of resistance to macrolides, lincosamides and streptogramins in Staphylococcus hominis strains isolated from clinical specimens.Folia microbiologica · 2016Article
- Pathophysiological Mechanisms of Staphylococcus Non-aureus Bone and Joint Infection: Interspecies Homogeneity and Specific Behavior of S. pseudintermedius.Frontiers in microbiology · 2016Article
- Antibiotic Susceptibility of Biofilm Cells and Molecular Characterisation of Staphylococcus hominis Isolates from Blood.PloS one · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Staphylococcus hominis is the third species of coagulase-negative staphylococci (CoNS) most frequently isolated from specimens of patients with hospital-acquired infections. Many infections caused by CoNS appeared to be associated with biofilms. Nevertheless, the knowledge of the ability of S. hominis to form a biofilm is limited. The aim of this study was to analyze the formation of the biofilm by 56 S. hominis strains isolated from clinical cases. The biofilm three-dimensional structure was reconstructed by confocal laser scanning microscopy. We found that most of S. hominis strains carried icaADBC genes encoding polysaccharide intercellular adhesin (PIA), which plays a crucial role in the formation of biofilms in staphylococci strains. However, only a half of the ica-positive strains had an ability to form a biofilm in vitro. In this study, we also accessed the sensitivity of biofilms of S. hominis strains to sodium metaperiodate, proteinase K and DNase. We found that polysaccharides and proteins are the major components of the extracellular matrix of the biofilm formed by S. hominis. DNase did not have a significant effect on biofilms, which suggested that nucleic acid plays a minor role in the mature biofilm.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.