Evidence map›Paper›PMID 24984814›Full record

ArticleChemical communications (Cambridge, England)2014

Sulfated quaternary amine lipids: a new class of inverse charge zwitterlipids.

Vincent J Venditto, Aaron Dolor, Aditya Kohli, Stefan Salentinig, Ben J Boyd, Francis C Szoka

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vincent J VendittoDepartment of Bioengineering and Therapeutic Sciences, School of Pharmacy, University of California San Francisco, San Francisco, CA 94143, USA.
Aaron Dolor
Aditya Kohli
Stefan Salentinig
Ben J Boyd
Francis C Szoka

Funding

PHARMACEUTICAL SCIENCES AND PHARMACOGENOMICST32GM007175 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, KROETZ, DEANNA L · 1985 to 2021
$7.1M
Targeted Drug Delivery to Surface Receptors.R01GM061851 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SZOKA, FRANCIS C. · 2001 to 2015
$3.5M
Rational Design of Viral-Mimetic Lipid Gene VectorsR01EB003008 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SZOKA, FRANCIS C. · 2003 to 2013
$3.2M
Do peptide mimetics of gp41 improve antibody-epitope interactions?F32AI095062 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VENDITTO, VINCENT JOSEPH · 2012 to 2014
$163k
NIAID NIH HHS 1F32AI095062NIAID NIH HHS F32 AI095062NIBIB NIH HHS EB-003008NIBIB NIH HHS R01 EB003008NIGMS NIH HHS R01 GM061851NIGMS NIH HHS T32 GM007175
6 · The paper itself

Abstract

We describe a new class of charge inverted zwitterionic sulfated lipids (AS) with a cationic quaternary amine anchored at the membrane interface and an anionic sulfate moiety extended into the aqueous phase. These lipids have exceptionally high transition temperatures and assemble into lipid aggregates when dispersed in aqueous solutions.

Indexed as

AminesCalorimetry, Differential ScanningLipidsSulfatesTransition TemperatureAminesLipidsSulfates

Identifiers

PMID24984814
PMCPMC4214375

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.