ArticleNMR in biomedicine2014
Oxygen-enhanced 3D radial ultrashort echo time magnetic resonance imaging in the healthy human lung.
Article in NMR in biomedicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Independent component analysis (ICA) applied to dynamic oxygen-enhanced MRI (OE-MRI) for robust functional lung imaging at 3 T.Magnetic resonance in medicine · 2024Article
- Feasibility of dynamic TMagnetic resonance in medicine · 2024Article
- Quantitative Imaging Metrics for the Assessment of Pulmonary Pathophysiology: An Official American Thoracic Society and Fleischner Society Joint Workshop Report.Annals of the American Thoracic Society · 2023Article
- Free-Breathing Phase-Resolved Oxygen-Enhanced Pulmonary MRI Based on 3D Stack-of-Stars UTE Sequence.Sensors (Basel, Switzerland) · 2022Article
- Self-gated 3D stack-of-spirals UTE pulmonary imaging at 0.55T.Magnetic resonance in medicine · 2022Article
- Oxygen-enhanced functional lung imaging using a contemporary 0.55 T MRI system.NMR in biomedicine · 2021Article
- Evaluation of pulmonary ventilation in COVID-19 patients using oxygen-enhanced three-dimensional ultrashort echo time MRI: a preliminary study.Clinical radiology · 2021Article
- Novel imaging techniques for cystic fibrosis lung disease.Pediatric pulmonology · 2021Review
- Novel Thoracic MRI Approaches for the Assessment of Pulmonary Physiology and Inflammation.Advances in experimental medicine and biology · 2021Article
- Pulmonary Functional Imaging for Lung Adenocarcinoma: Combined MRI Assessment Based on IVIM-DWI and OE-UTE-MRI.Frontiers in oncology · 2021Article
- Deep convolutional neural networks with multiplane consensus labeling for lung function quantification using UTE proton MRI.Journal of magnetic resonance imaging : JMRI · 2019Article
- "Structure-Function Imaging of Lung Disease Using Ultrashort Echo Time MRI".Academic radiology · 2019Review
- Structural and Functional Pulmonary Magnetic Resonance Imaging in Pediatrics-From the Neonate to the Young Adult.Academic radiology · 2019Review
- Simultaneous Evaluation of Lung Anatomy and Ventilation Using 4D Respiratory-Motion-Resolved Ultrashort Echo Time Sparse MRI.Journal of magnetic resonance imaging : JMRI · 2019Article
- Three-dimensional Isotropic Functional Imaging of Cystic Fibrosis Using Oxygen-enhanced MRI: Comparison with HyperpolarizedRadiology · 2019Article
- Pulmonary ventilation imaging in asthma and cystic fibrosis using oxygen-enhanced 3D radial ultrashort echo time MRI.Journal of magnetic resonance imaging : JMRI · 2018Article
- Retrospective respiratory self-gating and removal of bulk motion in pulmonary UTE MRI of neonates and adults.Magnetic resonance in medicine · 2017Article
- Hyperpolarized 129Xenon Magnetic Resonance Imaging to Quantify Regional Ventilation Differences in Mild to Moderate Asthma: A Prospective Comparison Between Semiautomated Ventilation Defect Percentage Calculation and Pulmonary Function Tests.Investigative radiology · 2017Article
- Pulmonary MRI of neonates in the intensive care unit using 3D ultrashort echo time and a small footprint MRI system.Journal of magnetic resonance imaging : JMRI · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The purpose of this work was to use 3D radial ultrashort echo time (UTE) MRI to perform whole-lung oxygen-enhanced (OE) imaging in humans. Eight healthy human subjects underwent two 3D radial UTE MRI acquisitions (TE = 0.08 ms): one while breathing 21% O2 and the other while breathing 100% O2. Scans were each performed over 5 min of free breathing, using prospective respiratory gating. For comparison purposes, conventional echo time (TE = 2.1 ms) images were acquired simultaneously during each acquisition using a radial " outward-inward" k-space trajectory. 3D percent OE maps were generated from these images. 3D OE maps showing lung signal enhancement were generated successfully in seven subjects (technical failure in one subject). Mean percent signal enhancement was 6.6% ± 1.8%, near the value predicted by theory of 6.3%. No significant enhancement was seen using the conventional echo time data, confirming the importance of UTE for this acquisition strategy. 3D radial UTE MRI shows promise as a method for OE MRI that enables whole-lung coverage and isotropic spatial resolution, in comparison to existing 2D OE methods, which rely on a less time-efficient inversion recovery pulse sequence. These qualities may help OE MRI become a viable low-cost method for 3D imaging of lung function in human subjects.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.