ArticleScientific reports2014
Ontogenesis of the HPI axis and molecular regulation of the cortisol stress response during early development in Dicentrarchus labrax.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 46 citations in OpenAlex.
- Acute exposure to the conspecific alarm substance and its intergenerational consequences in Astyanax bimaculatus (Linnaeus, 1758).Fish physiology and biochemistry · 2026Article
- Characterization of the corticotropin-releasing hormone family in largemouth bass and their expression profiles in response to feeding and acute and chronic heat stress.Journal of fish biology · 2026Article
- Heatwave duration modulates physio-biochemical responses in genetically improved farmed tilapia (Oreochromis niloticus) under simulated conditions.Fish physiology and biochemistry · 2026Article
- Molecular regulation of chronic stress responses in European sea bass,Frontiers in endocrinology · 2025Article
- Early-life challenge enhances cortisol regulation in zebrafish larvae.Biology open · 2024Article
- Screening and Identification of the Biomarkers Applied for the Evaluation of Acute and Chronic Thermal Tolerance Ability in Largemouth Bass (Animals : an open access journal from MDPI · 2024Article
- Knockout of theInternational journal of molecular sciences · 2021Article
- Predator-induced maternal effects determine adaptive antipredator behaviors via egg composition.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Parental selection for growth and early-life low stocking density increase the female-to-male ratio in European sea bass.Scientific reports · 2021Article
- Early Developmental Stress Affects Subsequent Gene Expression Response to an Acute Stress in Atlantic Salmon: An Approach for Creating Robust Fish for Aquaculture?G3 (Bethesda, Md.) · 2019Article
- Early-life manipulation of cortisol and its receptor alters stress axis programming and social competence.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Characterization and Expression Dynamics of Key Genes Involved in the Gilthead Sea Bream (Sparus aurata) Cortisol Stress Response during Early Ontogeny.Marine biotechnology (New York, N.Y.) · 2018Article
- Regulation of divergent cortisol responsiveness in European sea bass, Dicentrarchus labrax L.PloS one · 2018Article
- The effect of live feeds bathed with the red seaweed Asparagopsis armata on the survival, growth and physiology status of Sparus aurata larvae.Fish physiology and biochemistry · 2017Article
- α-MSH and melanocortin receptors at early ontogeny in European sea bass (Dicentrarchus labrax, L.).Scientific reports · 2017Article
- Transcriptomic changes in relation to early-life events in the gilthead sea bream (Sparus aurata).BMC genomics · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cortisol stress response and the molecular programming of the corticoid axis were characterized for the first time during early ontogeny in a Mediterranean marine teleost, the European sea bass (Dicentrarchus labrax). Sea bass embryos, pre-larvae and larvae at specific points of development were exposed to acute stressors and the temporal patterns of cortisol whole body concentrations and the expression of genes involved in corticosteroid biosynthesis, degradation and signaling were determined. Expression of genes (gr1, gr2, mr, crf) involved into the corticoid response regulation combined with histological data indicated that, although a cortisol stress response is evident for the first time around first feeding, a pattern becomes established in larvae at flexion until the formation of all fins. Moreover, mRNA transcript levels of 11β-hydroxylase and 11β-hsd2 showed a strong correlation with the whole body cortisol concentrations. Concluding, our data reveal the presence of an adaptive mechanism in European sea bass at early ontogeny enabling to cope with external stressful stimuli and provide a better insight into the onset and regulation of the stress response in this species.
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