ArticleParasite (Paris, France)2014
Detection of the amoeba Entamoeba gingivalis in periodontal pockets.
Article in Parasite (Paris, France), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07210814 (Pilot Study on the Activity of Commercially Available Mouthwashes Againgst Entamoeba Spp.), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pilot Study on the Activity of Commercially Available Mouthwashes Againgst Entamoeba Spp.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- RETRACTED: Association ofMedicina (Kaunas, Lithuania) · 2024Pooled it
- Current Global Status and the Epidemiology of Entamoeba gingivalis in Humans: A Systematic Review and Meta-analysis.Acta parasitologica · 2021Pooled it
- Microscopic Detection ofJournal of clinical medicine · 2026Article
- The association between Trichomonas tenax and Entamoeba gingivalis and periimplantitis and periodontitis.Clinical oral investigations · 2026Article
- Vientovirus capsid protein mimics autoantigens and contributes to autoimmunity in Sjögren's disease.Nature microbiology · 2025Article
- Investigation of Entamoeba gingivalis and Trichomonas tenax in gingivitis and periodontitis patients.BMC oral health · 2025Article
- Article
- Beyond Bacteria: The Impact of Protozoa on Periodontal Health.Microorganisms · 2025Review
- Impact of Periodontitis and Oral Dysbiosis Metabolites in the Modulation of Accelerating Ageing and Human Senescence.Metabolites · 2025Review
- The potential of antimicrobial peptides to treat oral infections and cancer.Frontiers in medicine · 2025Review
- Parasitological and molecular study ofArchives of Razi Institute · 2024Article
- Prevalence, socio-economic, and associated risk factors of oral cavity parasites in children with intellectual disability from Lorestan province, Iran.Frontiers in cellular and infection microbiology · 2024Article
- Evaluation of periodontitis parameters and plaque examination by microscopy: a report on 20 patients.Frontiers in dental medicine · 2024Article
- Pilot Study on the Prevalence ofMicroorganisms · 2023Article
- Molecular epidemiology and associated risk factors of oral cavity parasites in hemodialysis patients in western Iran.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023Article
- First molecular detection of Entamoeba gingivalis subtypes in individuals from Turkey.Pathogens and disease · 2023Article
- Widespread, human-associated redondoviruses infect the commensal protozoan Entamoeba gingivalis.Cell host & microbe · 2023Article
- Article
- Assessment ofArchives of Razi Institute · 2022Article
- Host prediction for disease-associated gastrointestinal cressdnaviruses.Virus evolution · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis is a public health issue, being one of the most prevalent diseases worldwide. However, the aetiology of the disease is still unclear: genetics of patients cannot explain the dispersed or isolated localisation of gingival pockets, while bacteria-based models are insufficient to distinguish gingivitis and periodontitis. The possible role of parasites in the establishment of periodontitis has been poorly studied until now. The aim of this project was to study a potential link between colonisation of gingival crevices by the amoeba Entamoeba gingivalis and periodontitis. In eight different dental clinics in France, samples were taken in periodontal pockets (72) or healthy sites (33), and submitted to microscopic observation and molecular identification by PCR with a new set of primers designed to specifically detect E. gingivalis. This blind sample analysis showed the strong sensitivity of PCR compared with clinical diagnosis (58/72 = 81%), and microscopy (51/65 = 78%). The results of this work show that the parasites detected by microscopy mainly - if not exclusively - belong to the species E. gingivalis and that the presence of the parasite is correlated with periodontitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.