ArticleAmerican journal of obstetrics and gynecology2015
Nonmedically indicated induction vs expectant treatment in term nulliparous women.
Article in American journal of obstetrics and gynecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Comparison of Maternal Labor-Related Complications and Neonatal Outcomes Following Elective Induction of Labor at 39 Weeks of Gestation vs Expectant Management: A Systematic Review and Meta-analysis.JAMA network open · 2023Pooled it
- Effects of induction of labor prior to post-term in low-risk pregnancies: a systematic review.JBI database of systematic reviews and implementation reports · 2019Pooled it
- Maternal and Neonatal Outcomes Associated with Amniotomy among Nulliparous Women Undergoing Labor Induction at Term.American journal of perinatology · 2021Trial
- Neonatal Outcomes Following Elective Induction of Labor at 39 Weeks: A Systematic Review.Cureus · 2025Review
- The rising tide: Trends in induction of labor at term over a 5-year period at a single centre.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Observational
- Outpatient elective induction of labour at 39 weeks' gestation (HOME INDUCTION): an open-label, randomised, controlled, phase III, non-inferiority trial.EClinicalMedicine · 2024Article
- Impacts of embracing 39-week elective induction across an entire labor and delivery unit.AJOG global reports · 2023Article
- Article
- Re-examining the Meis Trial for Evidence of False-Positive Results.Obstetrics and gynecology · 2020Article
- Induction of labor and postpartum blood loss.BMC pregnancy and childbirth · 2019Article
- Pregnancy outcomes of elective induction in low-risk term pregnancies: A propensity-score analysis.Medicine · 2019Observational
- Benefits and risks of induction of labor at 39 or more weeks in uncomplicated nulliparous women: a retrospective, observational study.Obstetrics & gynecology science · 2019Article
- Observational
- Nonmedically indicated induction in morbidly obese women is not associated with an increased risk of cesarean delivery.American journal of obstetrics and gynecology · 2017Article
- Timing of delivery and pregnancy outcomes in women with gestational diabetes.American journal of obstetrics and gynecology · 2016Article
- Term elective induction of labour and perinatal outcomes in obese women: retrospective cohort study.BJOG : an international journal of obstetrics and gynaecology · 2016Article
- A novel misoprostol delivery system for induction of labor: clinical utility and patient considerations.Drug design, development and therapy · 2015Review
Corrections and comments
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Authors and funding
17 authors at 18 institutions in 1 country.
Funding
Abstract
objectiveThe purpose of this study was to compare maternal and neonatal outcomes in nulliparous women with nonmedically indicated inductions at term vs those expectantly treated. STUDY
designData were obtained from maternal and neonatal charts for all deliveries on randomly selected days across 25 US hospitals over a 3-year period. A low-risk subset of nulliparous women with vertex nonanomalous singleton gestations who delivered 38 0/7 to 41 6/7 weeks were selected. Maternal and neonatal outcomes for nonmedically indicated induction within each week were compared with women who did not undergo nonmedically indicated induction during that week. Multivariable analysis was used to adjust for hospital, maternal age, race/ethnicity, body mass index, cigarette use, and insurance status.
resultsWe found 31,169 women who met our criteria. Neonatal complications were either less frequent with nonmedically indicated induction or no different between groups. Nonmedically indicated induction was associated with less frequent peripartum infections (odds ratio [OR], 0.39; 95% confidence interval [CI], 0.16-0.98) at 38 weeks of gestation and less frequent third- and fourth-degree lacerations (OR, 0.60; 95% CI, 0.42-0.86) and less frequent peripartum infections (OR, 0.66; 95% CI, 0.49-0.90) at 39 weeks of gestation. Nonmedically indicated induction was associated with a longer admission-to-delivery time by approximately 3-4 hours and increased odds of cesarean delivery at 38 (OR, 1.50; 95% CI, 1.08-2.08) and 40 weeks (OR, 1.30; 95% CI, 1.15-1.46) of gestation.
conclusionAt 39 weeks of gestation, nonmedically indicated induction is associated with lower maternal and neonatal morbidity than women who are expectantly treated.
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