Evidence map›Paper›PMID 24982917›Full record

Trial reportBioMed research international2014

Patient-controlled epidural levobupivacaine with or without fentanyl for post-cesarean section pain relief.

Shin-Yan Chen, Feng-Lin Liu, Yih-Giun Cherng, Shou-Zen Fan, Barbara L Leighton, Hung-Chi Chang, Li-Kuei Chen

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Post-caesarean analgesia: What is new?Indian journal of anaesthesia · 2017
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Shin-Yan ChenDepartment of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City 10361, Taiwan.
Feng-Lin LiuDepartment of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City 10361, Taiwan.
Yih-Giun CherngDepartment of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City 10361, Taiwan ; Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 10031, Taiwan.
Shou-Zen FanDepartment of Anesthesiology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10002, Taiwan.
Barbara L LeightonDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Hung-Chi ChangDepartment of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City 10361, Taiwan.
Li-Kuei ChenDepartment of Anesthesiology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 10002, Taiwan ; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA ; Department of Anesthesiology, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu City 30059, Taiwan.
Taipei Medical University-Shuang Ho Hospital · TWNational Taiwan University Hospital · TWTaipei Medical University · TWWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to compare the analgesic properties of levobupivacaine with or without fentanyl for patient-controlled epidural analgesia after Cesarean section in a randomized, double-blinded study.

methodsWe enrolled American Society of Anesthesiologists class I/II, full-term pregnant women at National Taiwan University Hospital who received patient-controlled epidural analgesia after Cesarean section between 2009 and 2010. Eighty women were randomly assigned into two groups. In group A, the 40 subjects received drug solutions made of 0.6 mg/ml levobupivacaine plus 2 mcg/ml fentanyl, and in group B the 40 subjects received 1 mg/ml levobupivacaine. Maintenance was self-administered boluses and a continuous background infusion.

resultsThere were no significant differences in the resting and dynamic pain scales and total volume of drug used between the two groups. Patient satisfaction was good in both groups.

conclusionOur study showed that pure epidural levobupivacaine can provide comparative analgesic properties to the levobupivacaine-fentanyl combination after Cesarean section. Pure levobupivacaine may serve as an alternative pain control regimen to avoid opioid-related adverse events in parturients.

Indexed as

Analgesia, EpiduralAnalgesia, Patient-ControlledCesarean SectionAdultBupivacaineFemaleFentanylHumansIncidenceLevobupivacainePain MeasurementPatient SatisfactionPostoperative PainPregnancyBupivacaineFentanylLevobupivacaine

Identifiers

PMID24982917
PMCPMC4055260
OpenAlexW2090653943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.