ArticleBioMed research international2014
Effect of low-level laser on bone defects treated with bovine or autogenous bone grafts: in vivo study in rat calvaria.
Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Photobiomodulation on critical bone defects of rat calvaria: a systematic review.Lasers in medical science · 2018Pooled it
- The dark art of light measurement: accurate radiometry for low-level light therapy.Lasers in medical science · 2016Pooled it
- In vitro investigation of the effect of laser on platelet-rich fibrins.BMC oral health · 2026Article
- Photobiomodulation Meets Mechanotransduction: Immune-Stromal Crosstalk in Orthodontic Remodeling.Biomedicines · 2025Review
- Comparison of the healing process of xenografts with three different sources in critical-size bone defects: An in vivo study.Journal of advanced periodontology & implant dentistry · 2024Article
- Photobiomodulation and Inorganic Bovine Bone in Guided Bone Regeneration: Histomorphometric Analysis in Rats.Journal of functional biomaterials · 2023Article
- Tissue Bioengineering with Fibrin Scaffolds and Deproteinized Bone Matrix Associated or Not with the Transoperative Laser Photobiomodulation Protocol.Molecules (Basel, Switzerland) · 2023Article
- Innovative Concepts and Recent Breakthrough for Engineered Graft and Constructs for Bone Regeneration: A Literature Systematic Review.Materials (Basel, Switzerland) · 2022Review
- Effect of Photobiomodulation Therapy Associated With Biphasic Phosphate Calcium on Bone Repair: A Histomorphometric Study in Rats.Journal of lasers in medical sciences · 2022Article
- Optimal Parameters of Laser Therapy to Improve Critical Calvarial Defects.Frontiers in physiology · 2022Article
- Bone repair assessment of critical size defects in rats treated with mineralized bovine bone (Bio-Oss®) and photobiomodulation therapy: a histomorphometric and immunohistochemical study.Lasers in medical science · 2021Article
- Simultaneous Treatment of Photobiomodulation and Demineralized Bone Matrix With Adipose-Derived Stem Cells Improve Bone Healing in an osteoporotic bone defect.Journal of lasers in medical sciences · 2021Article
- Effect of S53P4 bioactive glass and low-level laser therapy on calvarial bone repair in rats submitted to zoledronic acid therapy.Acta cirurgica brasileira · 2021Article
- Photobiomodulation Therapy Associated with Heterologous Fibrin Biopolymer and Bovine Bone Matrix Helps to Reconstruct Long Bones.Biomolecules · 2020Article
- Photobiomodulation Therapy (PBMT) Applied in Bone Reconstructive Surgery Using Bovine Bone Grafts: A Systematic Review.Materials (Basel, Switzerland) · 2019Review
- The influence of LLLT applied on applied on calvarial defect in rats under effect of cigarette smoke.Journal of applied oral science : revista FOB · 2019Article
- Quantitative assessment of rat bone regeneration using complex master-slave optical coherence tomography.Quantitative imaging in medicine and surgery · 2019Article
- Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study.Journal of applied oral science : revista FOB · 2018Article
- Evaluation of 660 nm LED light irradiation on the strategies for treating experimental periodontal intrabony defects.Lasers in medical science · 2016Article
- Intermittent administration of parathyroid hormone improves the repairing process of rat calvaria defects: A histomorphometric and radiodensitometric study.Medicina oral, patologia oral y cirugia bucal · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to histologically evaluate the effect of low-level laser (LLL) on the healing of critical size defects (CSD) in rat calvaria, filled with autogenous or inorganic bovine bone grafts.
methodsSixty rats were divided into 6 groups (n = 10): C (control-filled with blood clot), LLL (low-level laser-GaAlAs, λ 780 nm, 100 mW, 210 J/cm(2), Φ 0.05 cm(2); 6 J/point), AB (autogenous bone), ABL (autogenous bone + low-level laser), OB (inorganic bovine bone), and OBL (inorganic bovine bone + LLL). MATERIAL AND
methodsThe animals were killed after 30 days. Histological and histometric analyses were performed by light microscopy. Results. The groups irradiated with laser, LLL (47.67% ± 8.66%), ABL (39.15% ± 16.72%), and OBL (48.57% ± 28.22%), presented greater area of new bone formation than groups C (9.96% ± 4.50%), AB (30.98% ± 16.59%), and OB (11.36% ± 7.89%), which were not irradiated. Moreover, they were significantly better than group C (Kruskal-Wallis test followed by Dunn test, P < 0.05).
conclusionThe laser accelerated the healing of bone defects and the resorption of particles of the graft material.
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