ArticleFrontiers in oncology2014
Optimal design of anger camera for bremsstrahlung imaging: monte carlo evaluation.
Article in Frontiers in oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Role of nanoparticles in transarterial radioembolization with glass microspheres.Annals of nuclear medicine · 2022Article
- Effect of ME Collimator Characteristic, Energy Window Width, and Reconstruction Algorithm Selection on Imaging Performance of Yttrium-90: Simulation Study.Nuclear medicine and molecular imaging · 2019Article
- Practical reconstruction protocol for quantitative (90)Y bremsstrahlung SPECT/CT.Medical physics · 2016Article
- Review of SPECT collimator selection, optimization, and fabrication for clinical and preclinical imaging.Medical physics · 2015Review
- Editorial: Radioembolization in the Treatment of Liver Cancer: A Multidisciplinary Approach for Individualized Therapy.Frontiers in oncology · 2015Article
- Theranostic Imaging of Yttrium-90.BioMed research international · 2015Review
- Advances in SPECT for Optimizing the Liver Tumors Radioembolization Using Yttrium-90 Microspheres.World journal of nuclear medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A conventional Anger camera is not adapted to bremsstrahlung imaging and, as a result, even using a reduced energy acquisition window, geometric x-rays represent <15% of the recorded events. This increases noise, limits the contrast, and reduces the quantification accuracy. Monte Carlo (MC) simulations of energy spectra showed that a camera based on a 30-mm-thick BGO crystal and equipped with a high energy pinhole collimator is well-adapted to bremsstrahlung imaging. The total scatter contamination is reduced by a factor 10 versus a conventional NaI camera equipped with a high energy parallel hole collimator enabling acquisition using an extended energy window ranging from 50 to 350 keV. By using the recorded event energy in the reconstruction method, shorter acquisition time and reduced orbit range will be usable allowing the design of a simplified mobile gantry. This is more convenient for use in a busy catheterization room. After injecting a safe activity, a fast single photon emission computed tomography could be performed without moving the catheter tip in order to assess the liver dosimetry and estimate the additional safe activity that could still be injected. Further long running time MC simulations of realistic acquisitions will allow assessing the quantification capability of such system. Simultaneously, a dedicated bremsstrahlung prototype camera reusing PMT-BGO blocks coming from a retired PET system is currently under design for further evaluation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.