ArticleEvidence-based complementary and alternative medicine : eCAM2014
Effects of Nigella sativa (Habbatus sauda) Oil and Nicotine Chronic Treatments on Sperm Parameters and Testis Histological Features of Rats.
Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- Adverse Effects of Nicotine on Human Sperm Nuclear Proteins.The world journal of men's health · 2025Review
- Antimicrobial Properties and Therapeutic Potential of Bioactive Compounds inMolecules (Basel, Switzerland) · 2024Review
- Testicular tissue response following a 90-day subchronic exposure to HTP aerosols and cigarette smoke in rats.Toxicology research · 2023Article
- Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Review
- Soy Isoflavones Improve the Spermatogenic Defects in Diet-Induced Obesity Rats through Nrf2/HO-1 Pathway.Molecules (Basel, Switzerland) · 2019Article
- Ameliorative Effects ofThe Malaysian journal of medical sciences : MJMS · 2019Article
- Using Phytochemicals to Investigate the Activation of Nicotine Detoxification via Upregulation of CYP2A6 in Animal Models Exposed Tobacco Smoke Condensate by Intratracheal Instillation.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Effect of Thymoquinone on Reproductive Parameter in Morphine-treated Male Mice.Advanced biomedical research · 2018Article
- Protective effect of Nigella sativa seeds against spermatocyte chromosomal aberrations and genotoxicity induced by carbon tetrachloride in mice.Environmental science and pollution research international · 2017Article
- Male Infertility: The Effect of Natural Antioxidants and Phytocompounds on Seminal Oxidative Stress.Diseases (Basel, Switzerland) · 2017Review
- Investigating the effect ofAvicenna journal of phytomedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Twenty-four Sprague-Dawley male rats (7-9 weeks old, 200-250 g) were divided into Nicotine (N) (0.5 mg/100 g body weight (BW), Nicotine Control (NC) (saline, 0.1 mL/100 g BW), Habbatus sauda oil (HS) (6.0 μ L/100 g BW), and Habbatus sauda Control (HSC) (corn oil, 0.1 mL/100 g BW) groups and treated for 100 days. Sperm parameters and seminiferous tubules measurements were evaluated. The N showed a significantly lower sperm motility (1.03 ± 0.05 × 10(6) sperm/mL) and percentage of normal (82.61 ± 0.03%) and live (93.88 ± 0.01%) sperm, higher value for the seminiferous tubule (253.36 ± 1.83 μ m) and lumen (100.15 ± 2.38 μ m) diameters and spermatogonia (19.85 ± 0.39 μ m) and spermatocytes (33.37 ± 0.59 μ m) layers, and thinner spermatid-sperm layer (22.14 ± 0.71 μ m) than the NC (P < 0.05). The HS had significantly higher sperm motility (1.49 ± 0.04 × 10(6) sperm/mL) and percentage of normal (90.61 ± 0.01%) and live (96.98 ± 0.01%) sperm, smaller lumen diameter (67.53 ± 2.34 μ m) and thinner spermatogonia (17.67 ± 0.32 μ m) and wider spermatid-sperm (36.95 ± 0.79 μ m) layers than the HSC (P < 0.05). This research confirmed that nicotine reduced sperm motility and morphology of normal and live sperms and also affected the testis histology, while Habbatus sauda oil increased sperm quality and gave better testis histological features.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.