ArticleAntimicrobial agents and chemotherapy2014
High prevalence of blaCTX-M-1/IncI1/ST3 and blaCMY-2/IncI1/ST2 plasmids in healthy urban dogs in France.
Article in Antimicrobial agents and chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Article
- On the Difficulty to Detect Carbapenem Resistance in the Environment: Characterisation of Escherichia coli With Reduced Carbapenem Susceptibility Isolated in a French River.Environmental microbiology reports · 2025Article
- Interplay between bacterial clones and plasmids in the spread ofOne health (Amsterdam, Netherlands) · 2025Article
- ESBL- and pAmpC-producing Enterobacterales from Swedish dogs and cats 2017-2021: a retrospective study.Acta veterinaria Scandinavica · 2025Article
- Integration sites ofFrontiers in microbiology · 2025Article
- Comparison of IncK-Antibiotics (Basel, Switzerland) · 2024Article
- Staphylococcal skin infection isolates from dogs without recent antibiotic exposure are 100% susceptible to clindamycin.Frontiers in veterinary science · 2024Article
- Carriage of Extended Spectrum Beta Lactamase-ProducingAnimals : an open access journal from MDPI · 2023Article
- Article
- Genetic Diversity and New Sequence Types ofGenes · 2022Article
- Dynamics of extended-spectrum cephalosporin resistance genes in Escherichia coli from Europe and North America.Nature communications · 2022Article
- Clonal Dissemination of Extended-Spectrum Cephalosporin-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- Virulence determinant and antimicrobial resistance traits of Emerging MDR Shiga toxigenic E. coli in diarrheic dogs.AMB Express · 2022Article
- Exploring broilers and native fowls of Andaman and Nicobar Islands as a source of β-lactamase-producingFrontiers in veterinary science · 2022Article
- Antimicrobial Resistance Genes and Diversity of Clones among Faecal ESBL-ProducingAntibiotics (Basel, Switzerland) · 2021Article
- Global prevalence and molecular characterization of extended-spectrum β-lactamase producing-One health (Amsterdam, Netherlands) · 2021Article
- High β-lactam resistance in Gram-negative bacteria associated with kennel cough and cat flu in Egypt.Scientific reports · 2021Article
- Molecular Characteristics of Extraintestinal PathogenicMicroorganisms · 2020Article
- Low occurrence of extended-spectrum cephalosporinase producing Enterobacteriaceae and no detection of methicillin-resistant coagulase-positive staphylococci in healthy dogs in Sweden.Acta veterinaria Scandinavica · 2020Article
- Prevalence of Beta-Lactam and Quinolone/Fluoroquinolone Resistance inFrontiers in veterinary science · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the community, close contacts between humans and dogs may promote the transfer of extended-spectrum beta-lactamase/plasmidic AmpC cephalosporinase (ESBL/pAmpC) genes. Large-scale prevalence studies on ESBL/pAmpC carriage in dogs are rare, and data on ESBL/pAmpC plasmids are even more limited. Here, a considerable rate of 18.5% ESBL/pAmpC carriers was found among 368 unrelated healthy dogs in Paris, France. This prevalence is much higher than the one found in healthy humans in the same city (6%) but close to that recently reported in dogs in China (24.5%). All isolates were identified as Escherichia coli, except one Salmonella enterica and one Klebsiella pneumoniae isolate. The sequence type 131 (ST131) clone was rare (2/73 isolates). Interestingly, two plasmids (blaCTX-M-1/IncI1/ST3 and blaCMY-2/IncI1/ST2) were unexpectedly highly predominant, raising the question of their successful spread. Considering that CTX-M-1 was recently found to be equally as abundant as CTX-M-15 in healthy Parisian subjects, the question of dogs being a CTX-M-1 reservoir for humans is open. Such a high prevalence of the blaCMY-2/IncI1/ST2 plasmid may result from the use of cephalexin in veterinary medicine, as previously demonstrated experimentally. In all, our study points out healthy urban dogs as a potential source of ESBL/pAmpC genes that can further disseminate to the human community.
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