ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2014
Transforming the fight against tuberculosis: targeting catalysts of transmission.
Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Spatially targeted screening to reduce tuberculosis transmission in high-incidence settings.The Lancet. Infectious diseases · 2019Pooled it
- Transmission of Mycobacterium Tuberculosis in Households and the Community: A Systematic Review and Meta-Analysis.American journal of epidemiology · 2017Pooled it
- Potential impact of spatially targeted adult tuberculosis vaccine in Gujarat, India.Journal of the Royal Society, Interface · 2016Trial
- Airborne Mycobacterium tuberculosis inactivated by advanced photohydrolysis technology.Annals of clinical microbiology and antimicrobials · 2026Article
- Mycobacterium tuberculosis cough aerosol culture status associates with host characteristics and inflammatory profiles.Nature communications · 2024Article
- Usefulness of Xpert MTB/RIF and Xpert Ultra to Categorize Risk of Tuberculosis Transmission to Household Contacts.Open forum infectious diseases · 2024Article
- Tuberculosis Infectiousness is Associated with Distinct Clinical and Inflammatory Profiles.Research square · 2024Article
- Nanotechnological innovations in paediatric tuberculosis management: current trends and future prospects.Frontiers in drug delivery · 2023Review
- Characterizing tuberculosis transmission dynamics in high-burden urban and rural settings.Scientific reports · 2022Article
- Community-based referral for tuberculosis preventive therapy is effective for treatment completion.PLOS global public health · 2022Article
- Excess Risk of Tuberculosis Infection Among Extra-household Contacts of Tuberculosis Cases in an African City.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Article
- Cavitary tuberculosis: the gateway of disease transmission.The Lancet. Infectious diseases · 2020Review
- Social Mixing and Clinical Features Linked With Transmission in a Network of Extensively Drug-resistant Tuberculosis Cases in KwaZulu-Natal, South Africa.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Performance of a household tuberculosis exposure survey among children in a Latin American setting.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2019Article
- Exploring the Relevance of Green Space and Epidemic Diseases Based on Panel Data in China from 2007 to 2016.International journal of environmental research and public health · 2019Article
- Projected population-wide impact of antiretroviral therapy-linked isoniazid preventive therapy in a high-burden setting.AIDS (London, England) · 2019Article
- Plasma indoleamine 2,3-dioxygenase activity as a potential biomarker for early diagnosis of multidrug-resistant tuberculosis in tuberculosis patients.Infection and drug resistance · 2019Article
- Effect of malnutrition on radiographic findings and mycobacterial burden in pulmonary tuberculosis.PloS one · 2019Observational
- Building capacity for advances in tuberculosis research; proceedings of the third RePORT international meeting.Tuberculosis (Edinburgh, Scotland) · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The global tuberculosis control community has committed itself to ambitious 10-year targets. To meet these targets, biomedical advances alone will be insufficient; a more targeted public health tuberculosis strategy is also needed. We highlight the role of "tuberculosis transmission catalysts," defined as variabilities in human behavior, bacillary properties, and host physiology that fuel the propagation of active tuberculosis at the local level. These catalysts can be categorized as factors that increase contact rates, infectiousness, or host susceptibility. Different catalysts predominate in different epidemiological and sociopolitical settings, and public health approaches are likely to succeed only if they are tailored to target the major catalysts driving transmission in the corresponding community. We argue that global tuberculosis policy should move from a country-level focus to a strategy that prioritizes collection of data on key transmission catalysts at the local level followed by deployment of "catalyst-targeted" interventions, supported by strengthened health systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.