ArticleLasers in medical science2015
Inactivation of Aggregatibacter actinomycetemcomitans by two different modalities of photodynamic therapy using Toluidine blue O or Radachlorin as photosensitizers: an in vitro study.
Article in Lasers in medical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 43 citations in OpenAlex.
- Evaluation of antimicrobial photodynamic therapy with Butyl toluidine blue O for inactivation of Aggregatibacter actinomycetemcomitans biofilm.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- Effects of Antimicrobial Photosensitizers of Photodynamic Therapy (PDT) to Treat Periodontitis.Current pharmaceutical biotechnology · 2024Review
- Comparison of the antimicrobial reduction effect of photodynamic inactivation with the addition of chlorophyll and curcumin photosensitizer inF1000Research · 2023Article
- In vitro evaluation of physical and chemical parameters involved in aPDT of Aggregatibacter actinomycetemcomitans.Lasers in medical science · 2022Article
- Recent advances in innovative strategies for enhanced cancer photodynamic therapy.Theranostics · 2021Review
- Enhancement of Photodynamic Cancer Therapy by Physical and Chemical Factors.Angewandte Chemie (International ed. in English) · 2019Review
- Non-Invasive Photodynamic Therapy against -Periodontitis-causing Bacteria.Scientific reports · 2019Article
- Can Antimicrobial Photodynamic Therapy (aPDT) Enhance the Endodontic Treatment?Journal of lasers in medical sciences · 2016Review
- An In Vitro Comparison of Antimicrobial Effects of Curcumin-Based Photodynamic Therapy and Chlorhexidine, on Aggregatibacter actinomycetemcomitans.Journal of lasers in medical sciences · 2016Article
- Non-conventional therapeutics for oral infections.Virulence · 2015Review
- Clinical Approach of High Technology Techniques for Control and Elimination of Endodontic Microbiota.Journal of lasers in medical sciences · 2015Review
- Traditionally used herbal medicines with antibacterial effect onJournal of Indian Society of PeriodontologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) is one of the periodontopathogens strongly associated with aggressive periodontitis. The aim of this investigation was to compare the effect of laser and light-emitting diode on the photodynamic inactivation of A. actinomycetemcomitans. Eighty-four samples of bacterial suspensions (200 μL) were prepared and divided in seven groups: control group (no treatment), laser group (indium-gallium-aluminum-phosphate laser with wavelength of 662 ± 0.1 nm, energy density of 6 j/cm(2), and irradiation time of 34 s), light-emitting diode (LED) group (wavelength 625-635 nm, energy density 6 j/cm(2), time of irradiation 30 s), Toluidine blue O (TBO) group (0.1 mg/mL), Radachlorin group (0.1 %), Radachlorin + laser group (after pre-irradiation time of 10 min, laser was irradiated), and TBO + LED group (after preirradiation time of 10 min, LED was irradiated). Then, 100 μL of each sample was cultured in brain heart infusion (BHI) plates and incubated for 48-72 h in microaerophilic atmosphere for colony counting. Application of Radachlorin + laser resulted in a significant decrease in the concentration of A. actinomycetemcomitans (P values <0.05). Photodynamic therapy with laser + Radachlorin was more effective than that of LED + TBO in suppression of this microorganism (P value <0.05). Within the limits of this study, it can be concluded that photodynamic inactivation using laser and Radachlorin was more effective than that of LED and TBO in eradication of A. actinomycetemcomitans.
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