Evidence map›Paper›PMID 24981605›Full record

Trial reportTrials2014

Impact of drug reconciliation at discharge and communication between hospital and community pharmacists on drug-related problems: study protocol for a randomized controlled trial.

Xavier Pourrat, Clarisse Roux, Brigitte Bouzige, Valérie Garnier, Armelle Develay, Benoit Allenet, Martial Fraysse, Jean-Michel Halimi, Jacqueline Grassin, Bruno Giraudeau

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02006797 (Impact of Drug Reconciliation at Discharge and Pharmaceutical Communication Between Hospital and Community Pharmacists on Drug Related Problems), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02006797 naunknown statusnot on this map

Impact of Drug Reconciliation at Discharge and Pharmaceutical Communication Between Hospital and Community Pharmacists on Drug Related Problems: Study Protocol for a Cluster Randomized Cross-over Trial

TypeinterventionalSponsorUniversity Hospital, ToursRan2014 to 2015Enrolled1,176ConditionsTreatment ErrorArmsreconciliation
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Discharge planning from hospital.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Trial
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xavier PourratPharmacy Department, Pharm D, Tours University Hospital, 2 boulevard Tonnelle, 37044 Tours cedex 09, France. x.pourrat@chu-tours.fr.
Clarisse Roux
Brigitte Bouzige
Valérie Garnier
Armelle Develay
Benoit Allenet
Martial Fraysse
Jean-Michel Halimi
Jacqueline Grassin
Bruno Giraudeau

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients are at risk of drug-related problems (DRPs) at transition points during hospitalization. The community pharmacist (CP) is often the first healthcare professional patients visit after discharge. CPs lack sufficient information about the patient and so they may be unable to identify problems in medications, which may lead to dispensing the wrong drugs or dosage, and/or giving wrong information. We aim to assess the impact of a complex intervention comprising of medication reconciliation performed at discharge by a hospital pharmacist (HP) with communication between the HP and CP on DRPs during the seven days following discharge. METHODS/

designThe study is a cluster randomized crossover trial involving 46 care units (each unit corresponding to a cluster) in 22 French hospitals during two consecutive 14-day periods, randomly assigned as 'experimental' or 'control' (usual care) periods. We will recruit patients older than 18 years of age and visiting the same CP for at least three months. We will exclude patients with a hospital length of stay of more than 21 days, who do not return home or those in palliative care. During the experimental period, the HP will perform a medications reconciliation that will be communicated to the patient. The HP will inform the patient's CP about the patient's drug therapy (modification in home medication, acute drugs prescribed, nonprescription treatments, and/or lab results). The primary outcome will be a composite outcome of any kind of drug misuse during the seven days following discharge assessed at day seven (±2) post-discharge by a pharmacist in charge of the study who will contact both patients and CPs by phone. The secondary outcome will be unplanned hospitalizations assessed by phone contact at day 35 (±5) after discharge. We plan to recruit 1,176 patients. DISCUSSION: This study will assess the impact of a reconciliation of medications performed at patient discharge followed by communication between the HP and the patient's CP. It will allow for identifying the type of patients in France for which the intervention is most relevant.

trial registrationThis study was registered with ClinicalTrials.gov (number: NCT02006797) on 5 December 2013.

Indexed as

CommunicationCommunity Pharmacy ServicesInterinstitutional RelationsMedication ReconciliationPatient DischargePharmacistsPharmacy Service, HospitalResearch DesignClinical ProtocolsCooperative BehaviorCross-Over StudiesDrug InteractionsDrug-Related Side Effects and Adverse ReactionsFranceHumansPatient Care Team

Identifiers

PMID24981605
PMCPMC4226949

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.