ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2015
MiR-215/192 participates in gastric cancer progression.
Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- CircKIF5B Promotes Hepatocellular Carcinoma Progression by Regulating the miR-192 Family/XIAP Axis.Frontiers in oncology · 2022Article
- LncRNA XIST upregulates TRIM25 via negatively regulating miR-192 in hepatitis B virus-related hepatocellular carcinoma.Molecular medicine (Cambridge, Mass.) · 2021Article
- Evaluating the expression level of miR-9-5p and miR-192-5p in gastrointestinal cancer: introducing novel screening biomarkers for patients.BMC research notes · 2020Article
- MicroRNA‑192 inhibits cell proliferation and induces apoptosis in human breast cancer by targeting caveolin 1.Oncology reports · 2019Article
- Epigenetic Field Cancerization in Gastric Cancer: microRNAs as Promising Biomarkers.Journal of Cancer · 2019Article
- miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancer.International journal of molecular medicine · 2018Article
- Soft-shelled turtle peptide modulates microRNA profile in human gastric cancer AGS cells.Oncology letters · 2018Article
- SMG-1 inhibition by miR-192/-215 causes epithelial-mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling.Cancer medicine · 2018Article
- Profiling of circulating exosomal miRNAs in patients with Waldenström Macroglobulinemia.PloS one · 2018Article
- Non-Coding RNAs and Resistance to Anticancer Drugs in Gastrointestinal Tumors.Frontiers in oncology · 2018Review
- Prognostic value of microRNAs in gastric cancer: a meta-analysis.Oncotarget · 2017Article
- MicroRNA-215 acts as a tumor suppressor in breast cancer by targeting AKT serine/threonine kinase 1.Oncology letters · 2017Article
- Article
- Role of miRNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer.World journal of gastroenterology · 2016Review
- Potential Diagnostic, Prognostic and Therapeutic Targets of MicroRNAs in Human Gastric Cancer.International journal of molecular sciences · 2016Review
- miR-196b regulates gastric cancer cell proliferation and invasion via PI3K/AKT/mTOR signaling pathway.Oncology letters · 2016Article
- Emerging roles of non-coding RNAs in gastric cancer: Pathogenesis and clinical implications.World journal of gastroenterology · 2016Review
- Comparison of Prognostic MicroRNA Biomarkers in Blood and Tissues for Gastric Cancer.Journal of Cancer · 2016Review
- The expanding regulatory universe of p53 in gastrointestinal cancer.F1000Research · 2016Review
- miR-449a targets Flot2 and inhibits gastric cancer invasion by inhibiting TGF-β-mediated EMT.Diagnostic pathology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionGrowing evidence indicates that microRNAs (miRNAs) play critical roles in cancer progression. However, the role of miR-215 or miR-192 in gastric carcinogenesis remains unclear at this point. MATERIALS AND
methodsQuantitative real-time PCR analysis is used to detect the expression levels of miR-215 or -192. Matrigel invasion assay is used to explore the effects of miR-215 or -192 on gastric cancer cells invasion ability. Statistical analysis is carried out by SPSS 19.0 software.
resultsMiR-215/192 is significantly up-regulated in gastric cancer tissues from gastrectomy. The up-regulation of miR-215 or -192 was related with the clinical characteristics of gastric cancer, such as lymph node metastasis. Inhibition of miR-215/192 significantly suppressed gastric cancer cell invasion. Statistical analysis indicated that the expression of miR-215 or -192 may be a potential candidate biomarker for gastric cancer prognosis.
conclusionsThese data suggest that frequently up-regulated miR-215/192 in gastric cancer may participate in gastric cancer progression.
Indexed as
Identifiers
24981590What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.