ArticleWorld journal of surgery2014
Prevention of subcutaneous seroma formation in open ventral hernia repair using a new low-thrombin fibrin sealant.
Article in World journal of surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- The use of adjuncts to reduce seroma in open incisional hernia repair: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2018Pooled it
- Using quilting sutures in decreasing seroma formation after managing large ventral hernias: a comparative study.Hernia : the journal of hernias and abdominal wall surgery · 2019Trial
- Total endoscopic-assisted linea alba reconstruction (TESLAR) for treatment of umbilical/paraumbilical hernia and rectus abdominus diastasis is associated with unacceptable persistent seroma formation: a single centre experience.Hernia : the journal of hernias and abdominal wall surgery · 2020Article
- To Glue or Not to Glue? Analysis of Fibrin Glue for Split-thickness Skin Graft Fixation.Plastic and reconstructive surgery. Global open · 2019Article
- What Do We Know About the Chevrel Technique in Ventral Incisional Hernia Repair?Frontiers in surgery · 2019Review
- Onlay Technique in Incisional Hernia Repair-A Systematic Review.Frontiers in surgery · 2018Article
- The effect of TISSEEL fibrin sealant on seroma formation following complex abdominal wall hernia repair: a single institutional review and derived cost analysis.Hernia : the journal of hernias and abdominal wall surgery · 2015Article
- Complex ventral hernia repair with a human acellular dermal matrix and component separation: A case series.Annals of medicine and surgery (2012) · 2015Article
- Vital roles of stem cells and biomaterials in skin tissue engineering.World journal of stem cells · 2015Review
- Triple-Action Seroma Prevention Protocol in Subcutaneous Onlay Endoscopic Repair.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeroma formation is a frequent postoperative complication following open ventral hernia repair (OVHR), especially in cases requiring wide subcutaneous dissection (WSD). The aim of this study was to evaluate the effectiveness of a new low-thrombin fibrin sealant for seroma prevention.
methodsA total of 60 consecutive patients with median incisional hernias who required OVHR with WSD of at least 100 cm(2) were included in the prospective non-randomized study. The fibrin glue group (FG) comprised 30 patients who had undergone OVHR with sublay mesh placement as well as subcutaneous application of low-thrombin fibrin sealant. This cohort of patients was compared with a control group (CG) of 30 consecutive patients who had previously undergone OVHR without prevention of seroma formation with regard to outcome measures such as seroma formations and wound complications.
resultsThough the median extent of subcutaneous dead space was larger in the FG than in the CG (229 vs.174 cm(2); p = 0.012), seroma formation occurred in three of the FG versus 16 of the CG patients (p = 0.003). Postoperative wound complications occurred in two of the FG versus nine of the CG patients (p = 0.002). Four patients in the CG and none in the FG required re-operation within 30 days (p < 0.001).
conclusionThe use of a new low-thrombin fibrin glue demonstrated a protective effect against formation of seromas and decreased the rate of wound complications in OVHR, with consecutive shorter length of hospital stay (5.8 vs. 10.4 days; p = 0.04).
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