Evidence map›Paper›PMID 24979578›Full record

ArticlePsychosomatic medicine

Persistent depressive symptoms and pain after cardiac surgery.

Lynn V Doering, Belinda Chen, Anthony McGuire, Rebecca Cross Bodán, Michael R Irwin

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychosomatic medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00522717 (Enhancing Recovery After Cardiac Surgery), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00522717 nacompletednot on this map

Enhancing Recovery After Cardiac Surgery

TypeinterventionalSponsorUniversity of California, Los AngelesRan2005 to 2010Enrolled808ConditionsCoronary Artery Disease, DepressionArmsCognitive Behavioral Therapy (CBT), Usual Care
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lynn V DoeringFrom the University of California, Los Angeles, School of Nursing (L.V.D., B.C.), Los Angeles, California; University of California, Long Beach, School of Nursing (A.M.), Long Beach, California; California State University, Fullerton, School of Nursing (R.C.B.), Fullerton, California; and Cousins Center for Psychoneuroimmunology (M.R.I.), UCLA Semel Institute for Neuroscience, and Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA.
Belinda Chen
Anthony McGuire
Rebecca Cross Bodán
Michael R Irwin
University of California, Los Angeles · US

Funding

UCLA OLDER AMERICANS INDEPENDENCE CENTERP30AG028748 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MOORE, ALISON AHERN · 2006 to 2017
$9.8M
Enhancing Recovery After Cardiac SurgeryR01NR009228 · NINR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DOERING, LYNN VALERIE · 2005 to 2008
$1.9M
NIA NIH HHS P30 AG028748NINR NIH HHS 5R01NR009228-02NINR NIH HHS R01 NR009228
6 · The paper itself

Abstract

objectiveOur objectives were to describe trajectories of depressive symptoms and pain at hospital discharge and 6 weeks later and to examine the relationship of persistent depressive symptoms to pain.

methodsBefore and 6 weeks after hospital discharge, 251 patients undergoing cardiac surgery (mean [SD] age = 67.3 [9.5] years; 73% male) completed the Beck Depression Inventory and the Brief Pain Inventory (BPI). Patients were categorized into two groups based on the presence or absence of persistent depressive symptoms (Beck Depression Inventory score >10 at both times). Between-group differences in pain interference (BPI-INT) and pain severity (BPI-SEV) were evaluated using repeated-measures analysis of variance. Linear regressions were performed to determine if changes in depressive symptoms were related to BPI-INT and BPI-SEV, controlling for demographic and clinical data.

resultsPersistent (16.3%) or worsening depressive symptoms (15.3%) from hospital discharge to 6 weeks were observed; many experienced at least some persistent pain (BPI-INT 67.8%, BPI-SEV 47.8%). From discharge to 6 weeks, patients with persistent depressive symptoms sustained higher levels of BPI-INT (p < .001) and BPI-SEV (p < .003). In multivariate analysis, only changes in depressive symptoms, not clinical and demographic variables, were related to BPI-INT (p < .001) and BPI-SEV (p = .001).

conclusionsPersistent depressive symptoms are independently associated with continued pain up to 6 weeks after hospital discharge. Successful treatment of ongoing pain should include screening for depressive symptoms and initiation of appropriate treatment. TRIAL REGISTRATON: Clinicaltrials.gov Identifier: NCT00522717.

Indexed as

AgedCardiac Surgical ProceduresComorbidityDepressionFemaleFollow-Up StudiesHumansMaleMiddle AgedPainPain MeasurementPostoperative ComplicationsPostoperative PeriodRandomized Controlled Trials as Topic

Identifiers

PMID24979578
PMCPMC4139703
OpenAlexW2075059276

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.