Evidence map›Paper›PMID 24979394›Full record

Trial reportOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2014

Risk factors for loss of ipsilateral residual hearing after hybrid cochlear implantation.

Jonathan C Kopelovich, Lina A J Reiss, Jacob J Oleson, Emily S Lundt, Bruce J Gantz, Marlan R Hansen

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Electrocochleography in Cochlear Implant Users with Residual Acoustic Hearing: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Study on Recovery Strategy of Hearing Loss & SGN Regeneration Under Physical Regulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  6. Article
  7. Effects of Cochlear Implantation and Steroids on the Aging Guinea Pig Cochlea.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Impact of the round window membrane accessibility on hearing preservation in adult cochlear implantation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Article
  20. Current insights in noise-induced hearing loss: a literature review of the underlying mechanism, pathophysiology, asymmetry, and management options.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jonathan C Kopelovich*Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa; †Department of Otolaryngology Head and Neck Surgery, Oregon Health Science University, Portland, Oregon; and ‡Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa, U.S.A.
Lina A J Reiss
Jacob J Oleson
Emily S Lundt
Bruce J Gantz
Marlan R Hansen

Funding

Speech Production &LanguageP50DC000242 · NIDCD · UNIVERSITY OF IOWA · PI Bob McMurray · 1989 to 2026
$58.8M
XANTHINE OXIDASE PRODUCTS IN MODULATION OF ENDOTHELIAL DYSFUNCTIONM01RR000059 · NCRR · UNIVERSITY OF IOWA · PI ASHARE, ALIX · 1985 to 2007
$22.3M
Research Training Program in OtolaryngologyT32DC000040 · NIDCD · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R · 1993 to 2025
$5.4M
NCRR NIH HHS M01 RR000059NCRR NIH HHS RR00059NIDCD NIH HHS 2P50DC000242-26A1NIDCD NIH HHS P50 DC000242NIDCD NIH HHS T32 DC000040
6 · The paper itself

Abstract

objectiveResidual low-frequency acoustic hearing benefits cochlear implantees in difficult listening situations such as understanding speech in noise and music appreciation. Most subjects retain functional residual hearing in the operated ear. A small number of patients, however, will lose significant ipsilateral residual hearing after short-electrode cochlear implantation. The objectives of this retrospective series are to determine whether predisposition to hearing loss after implantation exists in a subset of patients and to assess the functional impact of this hearing loss on clinical measures of combined electric and acoustic hearing. STUDY

designRetrospective case series.

settingMulticenter clinical trial; tertiary care facility. PATIENTS: Hearing preservation cochlear implant recipients.

main outcome measureFrequency-averaged ipsilateral hearing loss at 1 year after activation.

resultsEighty-five patients from the Hybrid S8 FDA trial had serial postoperative audiometric measurements. Twenty-two of these patients, implanted at the home institution, provided additional medical data. Univariate analysis (Pearson's, Spearman's, Student's t test) showed that the severity of hearing loss at 1 year after activation was significantly correlated with age, male gender, and noise-induced hearing loss as the etiology of hearing impairment. A multivariate regression model corroborated these variables. No other medical factors were predictive. Clinical measures of speech perception (Consonant-Nucleus-Consonant and Hearing in Noise Test) worsened with hearing loss in ipsilateral but not bilateral listening conditions.

conclusionAge, male gender, and a history of noise-induced hearing loss correlate with the severity of hearing loss at 1 year after activation. Even the most severely affected patients benefit from bilateral electric and acoustic inputs.

Indexed as

Cochlear ImplantsHearingAdultAgedAged, 80 and overAuditory PerceptionCochlear ImplantationFemaleFunctional LateralityHearing LossHearing TestsHumansMaleMiddle AgedRetrospective StudiesRisk Factors

Identifiers

PMID24979394
PMCPMC4152771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.