ArticleMenopause (New York, N.Y.)2015
Extended maternal age at birth of last child and women's longevity in the Long Life Family Study.
Article in Menopause (New York, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Genetic associations with age of menopause in familial longevity.Menopause (New York, N.Y.) · 2019Pooled it
- The association of female and male infertility with telomere length (Review).International journal of molecular medicine · 2019Pooled it
- Association of LINE-1 RNA expressions in cell lines with longevity and reproductive lifespan.medRxiv : the preprint server for health sciences · 2025Article
- A National Institute on Aging workshop on the long-term effects of pregnancy on aging.Nature aging · 2025Article
- Article
- Association between late maternal age and age-related endophenotypes in the Long Life Family Study.Neuroscience letters · 2022Article
- Shortened Infant Telomere Length Is Associated with Attention Deficit/Hyperactivity Disorder Symptoms in Children at Age Two Years: A Birth Cohort Study.International journal of molecular sciences · 2022Article
- The Interrelationship Between Female Reproductive Aging and Survival.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Review
- Article
- Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age.Journal of women's health (2002) · 2021Article
- Association Between APOE Alleles and Change of Neuropsychological Tests in the Long Life Family Study.Journal of Alzheimer's disease : JAD · 2021Article
- Costs of reproduction and ageing in the human female.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Maternal age at last birth and leukocyte telomere length in a nationally representative population of perimenopausal and postmenopausal women.Menopause (New York, N.Y.) · 2020Article
- Pregnancy, postpartum and parity: Resilience and vulnerability in brain health and disease.Frontiers in neuroendocrinology · 2020Review
- Pregnancy and Lactation in a 67-Year-Old Elderly Gravida following Donor OocyteCase reports in obstetrics and gynecology · 2020Article
- Advanced Parental Age at Conception and Sex Affects Mitochondrial DNA Copy Number in Human and Fruit Flies.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
- Demographics, phenotypic health characteristics and genetic analysis of centenarians in China.Mechanisms of ageing and development · 2017Review
- Age-Based Reproductive Healthcare Stereotype Threat (HCST) as a Stressor Affecting Prenatal Mental Health in Pregnant Women of Advanced Maternal Age: Measurement, Process, Outcomes, and Interactions with Ethnicity/Race, SES, and Other Social Identities.Current epidemiology reports · 2017Article
- Telomere length is longer in women with late maternal age.Menopause (New York, N.Y.) · 2017Article
- Offspring schooling associated with increased parental survival in rural KwaZulu-Natal, South Africa.Social science & medicine (1982) · 2017Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveThis study investigated the association between maternal age at birth of last child and likelihood of survival to advanced age.
methodsThis was a nested case-control study using Long Life Family Study data. Three hundred eleven women who survived past the oldest 5th percentile of survival (according to birth cohort-matched life tables) were identified as cases, and 151 women who died at ages younger than the top 5th percentile of survival were identified as controls. A Bayesian mixed-effect logistic regression model was used to estimate the association between maternal age at birth of last child and exceptional longevity among these 462 women.
resultsWe found a significant association for older maternal age, whereby women who had their last child beyond age 33 years had twice the odds for survival to the top 5th percentile of survival for their birth cohorts compared with women who had their last child by age 29 years (age between 33 and 37 y: odds ratio, 2.08; 95% CI, 1.13 to 3.92; older age: odds ratio, 1.92; 95% CI, 1.03 to 3.68).
conclusionsThis study supports findings from other studies demonstrating a positive association between older maternal age and greater odds for surviving to an unusually old age.
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Registered trials
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