Evidence map›Paper›PMID 24977312›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2014

Substance use and hepatitis C: an ecological momentary assessment study.

Karran A Phillips, David H Epstein, Massoud Vahabzadeh, Mustapha Mezghanni, Jia-Ling Lin, Kenzie L Preston

Open access · greenAbstract read
In one paragraph

Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Karran A PhillipsNational Institute on Drug Abuse, Intramural Research Program, National Institutes of Health.
David H EpsteinNational Institute on Drug Abuse, Intramural Research Program, National Institutes of Health.
Massoud VahabzadehNational Institute on Drug Abuse, Intramural Research Program, National Institutes of Health.
Mustapha MezghanniJohns Hopkins Bayview Medical Center.
Jia-Ling LinNational Institute on Drug Abuse, Intramural Research Program, National Institutes of Health.
Kenzie L PrestonNational Institute on Drug Abuse, Intramural Research Program, National Institutes of Health.
Johns Hopkins University · US

Funding

Scientific Computing & Informatics Core (SCIC)ZIHDA000534 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI ERIKSON, RYEN · 2009 to 2025
$65.3M
Real-Time Assessment of Drug Use, Along with Mental States and EnvironmentsZIADA000499 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI EPSTEIN, DAVID · 2009 to 2025
$19.9M
Prevention of Relapse in AddictionZIADA000536 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI PRESTON, KENZIE · 2009 to 2018
$9.5M
Evaluation Of Treatments Of Opioid And Cocaine DependenceZIADA000175 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI PRESTON, KENZIE · 2009 to 2016
$7.4M
Intramural NIH HHS Z99 DA999999
6 · The paper itself

Abstract

objectiveThe objective of this study was to assess craving and mood related to opioid and cocaine use among asymptomatic hepatitis C virus (HCV)+ and HCV- methadone patients who have not started antiviral treatment.

methodsIn this 28-week prospective ecological momentary assessment (EMA) study, 114 methadone-maintained, heroin- and cocaine-abusing individuals reported from the field in real time on their mood, craving, exposure to drug-use triggers, and drug use via handheld computers.

resultsSixty-one percent were HCV+; none were overtly symptomatic or receiving HCV treatment. HCV status was not associated with age, sex, race, or past-30-day or lifetime heroin or cocaine use. In event-contingent EMA entries, HCV+ individuals more often attributed use to having been bored, worried, or sad; feeling uncomfortable; or others being critical of them compared with HCV- participants. In randomly prompted EMA entries, HCV+ participants reported significantly more exposure to drug-use triggers, including handling ≥$10, seeing cocaine or heroin, seeing someone being offered/use cocaine or heroin, being tempted to use cocaine, and wanting to see what would happen if they used just a little cocaine or heroin.

conclusionsHCV+ individuals experienced more negative moods and more often cited these negative moods as causes for drug use. HCV+ individuals reported greater exposure to environmental drug-use triggers, but they did not more frequently cite these as causes for drug use. The EMA data reported here suggest that HCV+ intravenous drug users may experience more labile mood and more reactivity to mood than HCV- intravenous drug users. The reason for the difference is not clear, but HCV status may be relevant to tailoring of treatment.

Indexed as

AffectCravingAdultAntiviral AgentsCocaine-Related DisordersFemaleHepatitis CHeroin DependenceHumansMaleMethadoneMiddle AgedProspective StudiesRisk-TakingAntiviral AgentsMethadone

Identifiers

PMID24977312
PMCPMC4575218
OpenAlexW2324727238

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.