Evidence map›Paper›PMID 24977303›Full record

ArticleEpidemiology and infection2015

H3N2 canine influenza virus with the matrix gene from the pandemic A/H1N1 virus: infection dynamics in dogs and ferrets.

H Moon, M Hong, J K Kim, B Seon, W Na, S J Park, D J An, H Y Jeoung, D J Kim, J M Kim and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

H MoonResearch Unit,Green Cross Veterinary Products, Yongin, Gyeonggi,Republic of Korea.
M HongViral Infectious Disease Research Center,Korea Research Institute of Bioscience and Biotechnology,Daejeon,Republic of Korea.
J K KimCollege of Pharmacy,Korea University,Sejong,Republic of Korea.
B SeonResearch Unit,Green Cross Veterinary Products, Yongin, Gyeonggi,Republic of Korea.
W NaViral Infectious Disease Research Center,Korea Research Institute of Bioscience and Biotechnology,Daejeon,Republic of Korea.
S J ParkViral Infectious Disease Research Center,Korea Research Institute of Bioscience and Biotechnology,Daejeon,Republic of Korea.
D J AnAnimal and Plant Quarantine Agency,Anyang, Gyeonggi,Republic of Korea.
H Y JeoungAnimal and Plant Quarantine Agency,Anyang, Gyeonggi,Republic of Korea.
D J KimViral Infectious Disease Research Center,Korea Research Institute of Bioscience and Biotechnology,Daejeon,Republic of Korea.
J M KimResearch Unit,Green Cross Veterinary Products, Yongin, Gyeonggi,Republic of Korea.
S H KimViral Infectious Disease Research Center,Korea Research Institute of Bioscience and Biotechnology,Daejeon,Republic of Korea.
R J WebbySt Jude Children's Research Hospital,Memphis, TN,USA.
R G WebsterSt Jude Children's Research Hospital,Memphis, TN,USA.
B K KangResearch Unit,Green Cross Veterinary Products, Yongin, Gyeonggi,Republic of Korea.
D SongViral Infectious Disease Research Center,Korea Research Institute of Bioscience and Biotechnology,Daejeon,Republic of Korea.
Korea Research Institute of Bioscience and Biotechnology · KRGreen Cross (South Korea) · KRAnimal and Plant Quarantine Agency · KRKorea University of Science and Technology · KRSt. Jude Children's Research Hospital · USGreen Cross International · USKorea University · KR

Funding

NIAID NIH HHS HHSN266200700005C
6 · The paper itself

Abstract

After an outbreak of pandemic influenza A/H1N1 (pH1N1) virus, we had previously reported the emergence of a recombinant canine influenza virus (CIV) between the pH1N1 virus and the classic H3N2 CIV. Our ongoing routine surveillance isolated another reassortant H3N2 CIV carrying the matrix gene of the pH1N1 virus from 2012. The infection dynamics of this H3N2 CIV variant (CIV/H3N2mv) were investigated in dogs and ferrets via experimental infection and transmission. The CIV/H3N2mv-infected dogs and ferrets produced typical symptoms of respiratory disease, virus shedding, seroconversion, and direct-contact transmissions. Although indirect exposure was not presented for ferrets, CIV/H3N2mv presented higher viral replication in MDCK cells and more efficient transmission was observed in ferrets compared to classic CIV H3N2. This study demonstrates the effect of reassortment of the M gene of pH1N1 in CIV H3N2.

Indexed as

AnimalsBase SequenceDog DiseasesDogsFerretsGenes, ViralInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeMadin Darby Canine Kidney CellsMolecular Sequence DataOrthomyxoviridae InfectionsPandemicsRecombination, GeneticViral Matrix ProteinsViral Matrix Proteinstransmission

Identifiers

PMID24977303
PMCPMC9507102
OpenAlexW2046107030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.