Evidence map›Paper›PMID 24977144›Full record

ArticleBioMed research international2014

Misidentification of Candida guilliermondii as C. famata among strains isolated from blood cultures by the VITEK 2 system.

Si Hyun Kim, Jeong Hwan Shin, Jeong Ha Mok, Shine Young Kim, Sae Am Song, Hye Ran Kim, Joong-Ki Kook, Young-Hyo Chang, Il Kwon Bae, Kwangha Lee

Abstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Identification of rare Candida species isolated from various clinical specimens: Comparison of different methods.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  2. Review
  3. Diagnosis and Treatment of Invasive Candidiasis.Antibiotics (Basel, Switzerland) · 2022
    Review
  4. The Flo Adhesin Family.Pathogens (Basel, Switzerland) · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Si Hyun KimDepartment of Laboratory Medicine, Inje University College of Medicine, Busan 614-735, Republic of Korea ; Paik Institute for Clinical Research, Inje University College of Medicine, Busan 614-735, Republic of Korea.
Jeong Hwan ShinDepartment of Laboratory Medicine, Inje University College of Medicine, Busan 614-735, Republic of Korea ; Paik Institute for Clinical Research, Inje University College of Medicine, Busan 614-735, Republic of Korea.ORCID 0000-0003-3960-6969
Jeong Ha MokDepartment of Internal Medicine, Pusan National University School of Medicine, Busan 602-739, Republic of Korea ; Biomedical Research Institute, Pusan National University School of Medicine, Busan 602-739, Republic of Korea.
Shine Young KimDepartment of Laboratory Medicine, Pusan National University School of Medicine, Busan 602-739, Republic of Korea.
Sae Am SongDepartment of Laboratory Medicine, Inje University College of Medicine, Busan 614-735, Republic of Korea.
Hye Ran KimDepartment of Laboratory Medicine, Inje University College of Medicine, Busan 614-735, Republic of Korea.
Joong-Ki KookDepartment of Oral Biochemistry, School of Dentistry, Chosun University, Gwangju 501-759, Republic of Korea.
Young-Hyo ChangKorean Collection for Type Cultures, Biological Resource Center, KRIBB, Daejeon 305-806, Republic of Korea.
Il Kwon BaeDepartment of Dental Hygiene, College of Medical and Life Science, Silla University, Busan 617-736, Republic of Korea.
Kwangha LeeDepartment of Internal Medicine, Pusan National University School of Medicine, Busan 602-739, Republic of Korea ; Biomedical Research Institute, Pusan National University School of Medicine, Busan 602-739, Republic of Korea ; Department of Internal Medicine, Pusan National University Hospital, 179, Gudeok-ro, Seo-gu, Busan 602-739, Republic of Korea.ORCID 0000-0001-9878-201X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction. The aim of this study was to differentiate between Candida famata and Candida guilliermondii correctly by using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) and gene sequencing. Methods. Twenty-eight Candida strains from blood cultures that had been identified as C. famata (N = 25), C. famata/C. guilliermondii (N = 2), and C. guilliermondii (N = 1) by the VITEK 2 system using the YST ID card were included. We identified these strains by MALDI-TOF MS and gene sequencing using the 28S rRNA and ITS genes and compared the results with those obtained by the VITEK 2 system. Results. All 28 isolates were finally identified as C. guilliermondii. Sequencing analysis of the 28S rRNA gene showed 99.80%-100% similarity with C. guilliermondii for all 28 strains. The ITS gene sequencing of the strains showed 98.34%-100% homology with C. guilliermondii. By MALDI-TOF, we could correctly identify 21 (75%) of 28 C. guilliermondii isolates. Conclusion. We should suspect misidentification when C. famata is reported by the VITEK 2 system, and we always should keep in mind the possibility of misidentification of any organism when an uncommon species is reported.

Indexed as

AlgorithmsCandidaCandidiasisClinical Laboratory TechniquesDiagnostic ErrorsDNA, FungalDNA, Ribosomal SpacerHumansMycological Typing TechniquesPhenotypePhylogenyReproducibility of ResultsRNA, Ribosomal, 18SSequence Analysis, DNASpecies SpecificitySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationDNA, FungalDNA, Ribosomal SpacerRNA, Ribosomal, 18S

Identifiers

PMID24977144
PMCPMC4058107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.