ReviewWorld journal of experimental medicine2014
Animal models of ex vivo lung perfusion as a platform for transplantation research.
Review in World journal of experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Early post-transplant ventilation and perfusion assessment using phase-resolved functional lung MRI.La Radiologia medica · 2026Article
- Research advances in consistency and variability inJournal of thoracic disease · 2026Review
- Cystatin C prevents tissue injury after lung transplantation.Life science alliance · 2026Article
- The Application and Challenges of Stem Cell-Derived Extracellular Vesicles in Inhalation Lung Injury.International journal of nanomedicine · 2026Review
- Contributions, bias, and research gaps in large animal ex vivo lung perfusion models: A systematic review.JHLT open · 2025Review
- Evaluation of Drug Permeation Enhancement by Using In Vitro and Ex Vivo Models.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Ischemia-reperfusion injury with a model of porcine whole-bloodFrontiers in transplantation · 2025Article
- Ex Vivo Organ Perfusion Systems for Disease Modeling and Therapeutic Applications in Small Animal Models.Journal of tissue engineering and regenerative medicine · 2025Review
- Changes in the levels of free sialic acid during ex vivo lung perfusion do not correlate with pulmonary function. Experimental model.BMC pulmonary medicine · 2023Article
- A Mouse Model of Orotracheal Intubation and Ventilated Lung Ischemia Reperfusion Surgery.Journal of visualized experiments : JoVE · 2022Article
- Ex Vivo Lung Perfusion: A Review of Current and Future Application in Lung Transplantation.Pulmonary therapy · 2022Review
- Emerging Paradigms in Bioengineering the Lungs.Bioengineering (Basel, Switzerland) · 2022Review
- Inflammation and Oxidative Stress in the Context of Extracorporeal Cardiac and Pulmonary Support.Frontiers in immunology · 2022Review
- Ex vivo normothermic perfusion of isolated segmental porcine bowel: a novel functional model of the small intestine.BJS open · 2021Article
- A translational rat model for ex vivo lung perfusion of pre-injured lungs after brain death.PloS one · 2021Article
- Ex-vivo delivery of monoclonal antibody (Rituximab) to treat human donor lungs prior to transplantation.EBioMedicine · 2020Article
- Porcine slaughterhouse lungs for ex vivo lung perfusion - a pilot project.American journal of translational research · 2020Article
- Article
- Lung regeneration: steps toward clinical implementation and use.Current opinion in anaesthesiology · 2017Review
- Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma.Magnetic resonance in medicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ex vivo lung perfusion (EVLP) is a powerful experimental model for isolated lung research. EVLP allows for the lungs to be manipulated and characterized in an external environment so that the effect of specific ventilation/perfusion variables can be studied independent of other confounding physiologic contributions. At the same time, EVLP allows for normal organ level function and real-time monitoring of pulmonary physiology and mechanics. As a result, this technique provides unique advantages over in vivo and in vitro models. Small and large animal models of EVLP have been developed and each of these models has their strengths and weaknesses. In this manuscript, we provide insight into the relative strengths of each model and describe how the development of advanced EVLP protocols is leading to a novel experimental platform that can be used to answer critical questions in pulmonary physiology and transplant medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.