Evidence map›Paper›PMID 24977108›Full record

ArticleCurrent nutrition reports2014

Genetic Variants in the FADS Gene: Implications for Dietary Recommendations for Fatty Acid Intake.

Rasika A Mathias, Vrindarani Pani, Floyd H Chilton

2 registry-linked trialsAbstract read
In one paragraph

Article in Current nutrition reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02962128 nacompletednot on this mapstarted 2016, after this paper: background citation

Role of PUFA-Gene Interactions in Health Disparities

TypeinterventionalSponsorWake Forest University Health SciencesRan2016 to 2021Enrolled80ConditionsFatty Acid-Gene InteractionsArmsHigh Linoleic Acid (LA) Diet, Low Linoleic Acid (LA) Diet
NCT04844034 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effects of a High Eicosapentaenoic Acid Multinutrient Supplement on Measures of Stress, Anxiety and Depression in Young Adults: a Randomised, Double-blind, Placebo-controlled Trial.

TypeinterventionalSponsorUniversity of RoehamptonRan2022 to 2023Enrolled94ConditionsAnxiety, DepressionArmsHigh-EPA multinutrient supplement., Placebo
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rasika A MathiasDivision of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21224, USA.
Vrindarani PaniDivision of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21224, USA.
Floyd H ChiltonThe Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest School of Medicine, Winston-Salem NC, 27157, USA ; Department of Physiology/Pharmacology, Wake Forest School of Medicine, Winston-Salem NC 27157, USA ; Molecular Medicine and Translational Sciences, Wake Forest School of Medicine, Winston-Salem NC 27157, USA.

Funding

The Wake Forest Center for Botanical Lipids and Inflammatory Disease PreventionP50AT002782 · NCCIH · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHILTON, FLOYD H · 2005 to 2014
$15.3M
NCCIH NIH HHS P50 AT002782
6 · The paper itself

Abstract

Unequivocally, genetic variants within the fatty acid desaturase (

Indexed as

arachidonic acidcardiovascular diseaseeicosanoidsfatty acid desaturase (FADS)genetic variantsinflammationnutritionpolyunsaturated fatty acidssingle nucleotide polymorphisms

Identifiers

PMID24977108
PMCPMC4070521

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.