Evidence map›Paper›PMID 24976670›Full record

ArticleJournal of applied polymer science. Applied polymer symposium2014

MS-Monitored Conjugation of Poly(ethylene glycol) Monomethacrylate to RGD Peptides.

Oleg I Bol'shakov, Emmanuel O Akala

Open access · greenAbstract read
In one paragraph

Article in Journal of applied polymer science. Applied polymer symposium, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Computer Optimization of Biodegradable Nanoparticles Fabricated by Dispersion Polymerization.International journal of environmental research and public health · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Oleg I Bol'shakovDepartment of Pharmaceutical Sciences/Center for Drug Research and Development (CDRD), College of Pharmacy, Howard University, Washington DC.
Emmanuel O AkalaDepartment of Pharmaceutical Sciences/Center for Drug Research and Development (CDRD), College of Pharmacy, Howard University, Washington DC.
Howard University · US

Funding

PROTEOMICS CORE FACILITYG12MD007597 · NIMHD · HOWARD UNIVERSITY · PI SOUTHERLAND, WILLIAM M. · 2012 to 2018
$14.8M
The District of Columbia Developmental Center for AIDS Research (DC D-CFAR)P30AI087714 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI GREENBERG, ALAN EDWARD · 2010 to 2014
$8.4M
EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT PROGRAM: REN*: PROSTATE BREAST CANCERC06RR020608 · NCRR · HOWARD UNIVERSITY · PI ADDERLEY-KELLY, BEATRICE · 2004 to 2004
$3.5M
RENOVATION THIRD FLOOR CHAUNCEY I. COOPER HALL-PHARMACYC06RR014469 · NCRR · HOWARD UNIVERSITY · PI LECCA, PEDRO J · 2000 to 2000
$1.0M
Biodegradable Polymeric Nanosphere Drug Delivery System For Cancer ChemotherapySC2CA138179 · NCI · HOWARD UNIVERSITY · PI AKALA, EMMANUEL O · 2008 to 2010
$333k
NCI NIH HHS SC2 CA138179NCRR NIH HHS C06 RR014469NCRR NIH HHS C06 RR020608NIAID NIH HHS P30 AI087714NIMHD NIH HHS G12 MD007597
6 · The paper itself

Abstract

Development of biologically active polymers is an active area of research due to their applications in varied and diverse fields of biomedical research: cell adhesion, tissue proliferation, and drug delivery. Recent advances in chemical modification allow fine-tuning of the properties of biomedical polymers to improve their applications: blood circulation half-life, stimuli-responsive degradation, site-specific targeting, drug loading, etc. In this article, convergent synthesis of polymerizable macromonomers bearing a site-specific ligand (RGD peptide) using a low molecular weight MA-poly(ethylene glycols) (PEGs) is presented. The method affords macromonomers useful as the starting materials to produce biomedical polymers. We found matrix assisted laser desorption/ionization mass spectromerty convenient in monitoring the conjugation process via step-by-step following of PEG modification.

Indexed as

biomaterialscopolymersdrug delivery systemsmolecular recognitionnanostructured polymers

Identifiers

PMID24976670
PMCPMC4071956
OpenAlexW2090444147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.