Evidence map›Paper›PMID 24976647›Full record

ArticleThe Psychological record2014

Repeated Acquisition in the Morris Swim Task: Effects of MDMA, Methamphetamine and Methylphenidate.

Mark Galizio, Bridget D Byrd, Andrea M Robinson, Andrew Hawkey, Rebecca Rayburn-Reeves, L Brooke April

Abstract read
In one paragraph

Article in The Psychological record, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mark GalizioDepartment of Psychology, University of North Carolina Wilmington.
Bridget D ByrdDepartment of Psychology, University of North Carolina Wilmington.
Andrea M RobinsonDepartment of Psychology, University of North Carolina Wilmington.
Andrew HawkeyDepartment of Psychology, University of North Carolina Wilmington.
Rebecca Rayburn-ReevesDepartment of Psychology, University of North Carolina Wilmington.
L Brooke AprilDepartment of Psychology, University of North Carolina Wilmington.

Funding

Drugs of Abuse and Memory SpanR15DA029252 · NIDA · UNIVERSITY OF NORTH CAROLINA WILMINGTON · PI GALIZIO, JOSEPH MARK · 2010 to 2016
$682k
DRUGS OF ABUSE AND COMPLEX BEHAVIORR15DA012879 · NIDA · UNIVERSITY OF NORTH CAROLINA WILMINGTON · PI GALIZIO, JOSEPH MARK · 2000 to 2003
$255k
NIDA NIH HHS R15 DA012879NIDA NIH HHS R15 DA029252
6 · The paper itself

Abstract

Acute effects of methylenedioxymethamphetamine (MDMA), methamphetamine (MA) and methylphenidate (MPD) were studied using a within-subject, repeated acquisition/performance procedure adapted to the Morris Swim Task. To investigate place learning, the acquisition component consisted of a hidden platform that varied in location across experimental sessions. As a control for drug effects not specific to acquisition, a performance component was included in which the hidden platform was in the same pool location in every experimental session. All three drugs increased escape latencies and swim distances in dose-dependent fashion. However, impairment in the acquisition component was generally observed only at doses that also produced impairment in the performance component, suggesting that effects were not selective to place learning. None of the drugs produced enhancement of learning or performance at any dose. Taken together, the results suggest that acute exposure to these psychomotor stimulants produce global impairment of performance in the Morris task, rather than specific deficits in place learning.

Indexed as

MDMAMethamphetamineMethylphenidateMorris Swim TaskSpatial Learning

Identifiers

PMID24976647
PMCPMC4066990

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.