Evidence map›Paper›PMID 24976645›Full record

ArticleJournal of fluorine chemistry2014

Design and formulation of nanoemulsions using 2-(poly(hexafluoropropylene oxide)) perfluoropropyl benzene in combination with linear perfluoro(polyethylene glycol dimethyl ether).

Gregory A Mountain, Benson J Jelier, Christina Bagia, Chadron M Friesen, Jelena M Janjic

Abstract read
In one paragraph

Article in Journal of fluorine chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gregory A MountainDepartment of Chemistry, Saint Francis University, Loretto, PA, 15940, USA.
Benson J JelierDepartment of Chemistry, Trinity Western University, Langley, BC, Canada V2Y 1Y1.
Christina BagiaGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, 15282, USA.
Chadron M FriesenDepartment of Chemistry, Trinity Western University, Langley, BC, Canada V2Y 1Y1 ; Department of Chemistry, Simon Fraser University, Burnaby, BC, Canada V5A 1S6.
Jelena M JanjicGraduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA, 15282, USA.

Funding

A Joint Computational/Experimental Biomedical Summer Research Program for UndergrR25DA032519 · NIDA · DUQUESNE UNIVERSITY · PI EVANSECK, JEFFREY D, MADURA, JEFFRY D. · 2011 to 2015
$418k
Dual Mode Nanoemulsions for 19F MRI and Fluorescence DetectionR41EB009618 · NIBIB · CELSENSE, INC. · PI JANJIC, JELENA M · 2009 to 2009
$132k
NIBIB NIH HHS R41 EB009618
6 · The paper itself

Abstract

This is the first report where PFPAE aromatic conjugates and perfluoro(polyethylene glycol dimethyl ether) are combined and formulated as nanoemulsions with droplet size below 100 nm. A perfluoropolyalkylether (PFPAE) aromatic conjugate, 2-(poly(hexafluoropropylene oxide)) perfluoropropyl benzene, was used as fluorophilic-hydrophilic diblock (FLD) aimed at stabilizing perfluoro(polyethylene glycol dimethyl ether) nanoemulsions. Its effects on colloidal behaviors in triphasic (organic/fluorous/aqueous) nanoemulsions were studied. The addition of FLD construct to fluorous phase led to decrease in PFPAE nanoemulsion droplet size to as low as 85 nm. Prepared nanoemulsions showed high colloidal stability. Our results suggest that these materials represent viable novel approach to fluorous colloid systems design with potential for biomedical and synthetic applications.

Indexed as

fluorousmicrofluidizationnanoemulsionsperfluoro(polyethylene glycol dimethyl ether)PFPAEsPFPEs

Identifiers

PMID24976645
PMCPMC4071295

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.