Evidence map›Paper›PMID 24976608›Full record

ArticleJournal of magnetic resonance imaging : JMRI2015

Numerical evaluation of image homogeneity, signal-to-noise ratio, and specific absorption rate for human brain imaging at 1.5, 3, 7, 10.5, and 14T in an 8-channel transmit/receive array.

Zhipeng Cao, Joshua Park, Zang-Hee Cho, Christopher M Collins

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Magnetic resonance imaging.Science advances · 2026
    Review
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  17. RF Coil Setup forFrontiers in neurology · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhipeng CaoDepartment of Bioengineering, Pennsylvania State University, Hershey, PA, USA.
Joshua Park
Zang-Hee Cho
Christopher M Collins

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
High Field MRI: Limitations and SolutionsR01EB000454 · NIBIB · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI COLLINS, CHRISTOPHER M · 2002 to 2012
$11.9M
High-Performance High-Field Parallel MRI.R01EB002568 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SODICKSON, DANIEL K · 2003 to 2014
$4.8M
RF Technology Innovation for Advancing High Field MR.R01EB011551 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COLLINS, CHRISTOPHER M · 2011 to 2014
$2.7M
MR Physics Simulation Package for Pulse, Sequence, and Hardware DesignR01EB006563 · NIBIB · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI COLLINS, CHRISTOPHER M · 2007 to 2009
$780k
NIBIB NIH HHS P41 EB017183NIBIB NIH HHS R01 EB000454NIBIB NIH HHS R01 EB002568NIBIB NIH HHS R01 EB006563NIBIB NIH HHS R01 EB011551
6 · The paper itself

Abstract

purposeTo predict signal-to-noise ratio (SNR) trends and absorbed energy in magnetic resonance imaging (MRI) of the brain up to 14T. MATERIALS AND

methodsA human head in an eight-channel transmit/receive coil was simulated with Maxwell and Bloch equations to determine excitation homogeneity with radiofrequency (RF) shimming, image homogeneity, SNR, and absorbed energy in MRI from 1.5 to 14T considering realistic field distributions and relaxation properties.

resultsRF shimming alone achieved a standard deviation in excitation flip angle less than 10° in mid-brain up to 14T, but produced a small region with low excitation on a lower slice. Current reconstruction methods may produce shading artifacts at 14T. SNR increases with a greater-than-linear rate for gradient recalled echo (GRE) sequences having short (2 msec) echo time (TE) and long relaxation time (TR) (∼2.3-fold increase from 7T to 14T), but a less-than-linear rate if TE is 10 msec (∼1.6-fold increase from 7T to 14T). Depending on the sequence, SNR per square root of imaging time may produce a less-than-linear increase with B0 . Whole-head absorbed energy shows a less-than-quadratic increase with B0 (1.7-fold increase from 7T to 14T).

conclusionNumerical simulations indicate that with proper preparation and precautions, imaging of the human brain at up to 14T could be performed safely, with advantages in SNR.

Indexed as

Absorption, RadiationModels, NeurologicalBrainComputer-Aided DesignComputer SimulationEquipment DesignEquipment Failure AnalysisHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingRadiation DosageReproducibility of ResultsSensitivity and SpecificitySignal-To-Noise RatioBloch simulationFDTDhigh-field MRIRF heatingSARsignal-to-noise ratio

Identifiers

PMID24976608
PMCPMC4277736

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.