Evidence map›Paper›PMID 24976087›Full record

SynthesisInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

Cerebral arterial fenestrations.

Daniel L Cooke, Charles E Stout, Warren T Kim, Akash P Kansagra, John Paul Yu, Amy Gu, Nicholas P Jewell, Steven W Hetts, Randall T Higashida, Christopher F Dowd and 1 more

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 99 citations in OpenAlex.

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  6. Multichannel internal carotid artery: congenital or acquired pattern?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  18. Small basilar artery fenestration mimicking an aneurysm.Surgical and radiologic anatomy : SRA · 2024
    Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Daniel L CookeDepartment of Radiology & Biomedical Imaging, University of California; San Francisco, CA, USA - daniel.cooke@ucsf.edu.
Charles E StoutDepartment of Radiology & Biomedical Imaging, University of California; San Francisco, CA, USA.
Warren T KimDepartment of Radiology & Biomedical Imaging, University of California; San Francisco, CA, USA.
Akash P KansagraDepartment of Radiology & Biomedical Imaging, University of California; San Francisco, CA, USA.
John Paul YuDepartment of Radiology & Biomedical Imaging, University of California; San Francisco, CA, USA.
Amy GuUniversity of California; Berkeley, CA, USA.
Nicholas P JewellUniversity of California; Berkeley, CA, USA.
Steven W HettsDepartment of Radiology & Biomedical Imaging, University of California; San Francisco, CA, USA.
Randall T HigashidaDepartment of Radiology & Biomedical Imaging, University of California; San Francisco, CA, USA.
Christopher F DowdDepartment of Radiology & Biomedical Imaging, University of California; San Francisco, CA, USA.
Van V HalbachDepartment of Radiology & Biomedical Imaging, University of California; San Francisco, CA, USA.
University of California, San Francisco · USUniversity of California, Berkeley · USUniversity of California System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arterial fenestrations are an anatomic variant with indeterminate significance. Given the controversy surrounding fenestrations we sought their prevalence within our practice along with their association with other cerebrovascular anomalies. We retrospectively reviewed 10,927 patients undergoing digital subtraction angiography between 1992 and 2011. Dictated reports were searched for the terms "fenestration" or "fenestrated" with images reviewed for relevance, yielding 228 unique cases. A Medline database search from February 1964 to January 2013 generated 304 citations, 127 cases of which were selected for analysis. Cerebral arterial fenestrations were identified in 228 patients (2.1%). At least one aneurysm was noted in 60.5% of patients, with an aneurysm arising from the fenestration in 19.6% of patients. Aneurysmal subarachnoid hemorrhage or non-aneurysmal subarachnoid hemorrhage were present in 60.1% and 15.8%, respectively. For the subset of patients with an aneurysm arising directly from a fenestration relative to those patients with an aneurysm not immediately associated with a fenestration, the prevalence of aneurysmal subarachnoid hemorrhage was 66.7% vs. 58.6% (p = 0.58). Fenestrations were more often within the posterior circulation (73.2%) than the anterior circulation (24.6%), though there was no difference in the prevalence of aneurysms within these groups (61.1% vs. 60.7%, p = 1.0). Cerebral arterial fenestrations are an anatomic variant more often manifesting at the anterior communicating arterial complex and basilar artery and with no definite pathological relationship with aneurysms.

Indexed as

AdultCentral Nervous System Vascular MalformationsCerebral AngiographyCerebral ArteriesComorbidityFemaleHumansIntracranial AneurysmMaleMiddle AgedRisk FactorsSubarachnoid Hemorrhageanatomyaneurysmfenestrationstrokesubarachnoid hemorrhage

Identifiers

PMID24976087
PMCPMC4178766
OpenAlexW2313748702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.