Evidence map›Paper›PMID 24975625›Full record

ReviewChild and adolescent psychiatric clinics of North America2014

Omega-3 fatty acid and nutrient deficits in adverse neurodevelopment and childhood behaviors.

Rachel V Gow, Joseph R Hibbeln

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Child and adolescent psychiatric clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 116 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Observational
  15. Article
  16. Obesogens: a unifying theory for the global rise in obesity.International journal of obesity (2005) · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Rachel V GowSection of Nutritional Neurosciences, Laboratory of Membrane Biochemistry and Biophysics, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, 31 Center Drive, Building 31, Room 1B54, Rockville, MD 20892, USA.
Joseph R HibbelnSection of Nutritional Neurosciences, Laboratory of Membrane Biochemistry and Biophysics, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 3N-01, Rockville, MD 20892, USA. Electronic address: jhibbeln@mail.nih.gov.
National Institute on Alcohol Abuse and Alcoholism · USNational Institutes of Health · US

Funding

Essential Fatty Acids In Psychiatric DisordersZIAAA000115 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI HIBBELN, JOSEPH · 2009 to 2020
$7.8M
Intramural NIH HHS ZIA AA000115
6 · The paper itself

Abstract

Nutritional insufficiencies of omega-3 highly unsaturated fatty acids (HUFAs) may have adverse effects on brain development and neurodevelopmental outcomes. A recent meta-analysis reported a small to modest effect size for the efficacy of omega-3 in youth. Several controlled trials of omega-3 HUFAs combined with micronutrients show sizable reductions in aggressive, antisocial, and violent behavior in youth and young adult prisoners. Studies of HUFAs in youth, however, remain lacking. As the evidence base for omega-3 HUFAs as potential psychiatric treatment develops, dietary adjustments to increase omega-3 and reduce omega-6 HUFA consumption are sensible recommendations based on general health considerations.

Indexed as

BrainFatty Acids, Omega-3MalnutritionMental DisordersAdolescentAdultAnimalsChildChild BehaviorDietDietary SupplementsHumansMeta-Analysis as TopicRandomized Controlled Trials as TopicReview Literature as TopicTreatment OutcomeFatty Acids, Omega-3Arachidonic acidAttention-deficit/hyperactivity disorderChild neurodevelopmentConduct disorderDocosahexaenoic acidEicosapentaenoic acidLearning disordersOmega-3 fatty acids

Identifiers

PMID24975625
PMCPMC4175558
OpenAlexW1989377809

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.