ArticleBrain structure & function2015
The superior paraolivary nucleus shapes temporal response properties of neurons in the inferior colliculus.
Article in Brain structure & function, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Forward masking in the inferior colliculus: Dynamics of discharge-rate recovery after narrowband noise maskers.The Journal of the Acoustical Society of America · 2025Article
- A Subcortical Model for Auditory Forward Masking with Efferent Control of Cochlear Gain.eNeuro · 2024Article
- Spatial-dependent suppressive aftereffect produced by a sound in the rat's inferior colliculus is partially dependent on local inhibition.Frontiers in neuroscience · 2023Article
- Nicotinic acetylcholine receptor subunit αJournal of neurophysiology · 2019Article
- Subcortical pathways: Towards a better understanding of auditory disorders.Hearing research · 2018Review
- Cellular Computations Underlying Detection of Gaps in Sounds and Lateralizing Sound Sources.Trends in neurosciences · 2017Review
- The organization of frequency and binaural cues in the gerbil inferior colliculus.The Journal of comparative neurology · 2017Article
- Deleting the HCN1 Subunit of Hyperpolarization-Activated Ion Channels in Mice Impairs Acoustic Startle Reflexes, Gap Detection, and Spatial Localization.Journal of the Association for Research in Otolaryngology : JARO · 2017Article
- Octopus Cells in the Posteroventral Cochlear Nucleus Provide the Main Excitatory Input to the Superior Paraolivary Nucleus.Frontiers in neural circuits · 2017Article
- Forward masking in the superior paraolivary nucleus of the rat.Brain structure & function · 2017Article
- Auditory deficits of Kcna1 deletion are similar to those of a monaural hearing impairment.Hearing research · 2015Article
- Yes, there is a medial nucleus of the trapezoid body in humans.Frontiers in neuroanatomy · 2015Review
- Development of glycinergic innervation to the murine LSO and SPN in the presence and absence of the MNTB.Frontiers in neural circuits · 2014Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
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Abstract
The mammalian superior paraolivary nucleus (SPON) is a major source of GABAergic inhibition to neurons in the inferior colliculus (IC), a well-studied midbrain nucleus that is the site of convergence and integration for the majority ascending auditory pathways en route to the cortex. Neurons in the SPON and IC exhibit highly precise responses to temporal sound features, which are important perceptual cues for naturally occurring sounds. To determine how inhibitory input from the SPON contributes to the encoding of temporal information in the IC, a reversible inactivation procedure was conducted to silence SPON neurons, while recording responses to amplitude-modulated tones and silent gaps between tones in the IC. The results show that SPON-derived inhibition shapes responses of onset and sustained units in the IC via different mechanisms. Onset neurons appear to be driven primarily by excitatory inputs and their responses are shaped indirectly by SPON-derived inhibition, whereas sustained neurons are heavily influenced directly by transient offset inhibition from the SPON. The findings also demonstrate that a more complete dissection of temporal processing pathways is critical for understanding how biologically important sounds are encoded by the brain.
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