Evidence map›Paper›PMID 24973840›Full record

Trial reportIndian heart journal

A multicentre retrospective study to understand anti-platelet treatment patterns and outcomes of acute coronary syndrome patients in India (TRACE).

Upendra Kaul, K K Sethi, Jamshed Dalal, Keyur Parikh, M S Hiremath, Ajit S Mullasari, Tiny Nair, P S Sandhu, Bhavesh Kotak

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Upendra KaulExecutive Director and Dean Cardiology, Escorts Heart Institute and Fortis Group of Hospitals, Okhla, New Delhi 110025, India. Electronic address: Kaul.upendra@gmail.com.
K K SethiChairman and Managing Director, Director of Cardiology, Delhi Heart and Lung Institute, Panchkuian Road, New Delhi, India.
Jamshed DalalDirector, Centre for Cardiac Sciences, Kokilaben Dhirubhai Ambani Hospital, Four Bungalows, Andheri (W), Mumbai 400053, Maharashtra, India.
Keyur ParikhChairman, Care Institute of Medical Sciences and Hospital, Off Science City Road, Sola, Ahmedabad 380060, Gujarat, India.
M S HiremathDirector, Cath Lab, Ruby Hall Clinic, Sasoon Road, Pune 411001, Maharashtra, India.
Ajit S MullasariDirector, Cardiology, Madras Medical Mission, J.J. Nagar, Mogappair, Chennai 600037, Tamil Nadu, India.
Tiny NairHead of the Dept, Cardiology, TRS Hospital, Trivandrum, Kerala, India.
P S SandhuAssociate Professor, Department of Cardiology, GGS Medical College, Faridkot 151203, Punjab, India.
Bhavesh KotakVice President, Medical Affairs & Regulatory, AstraZeneca Pharma India Ltd. 'Avishkar', P.B. No. 2483, Off Bellary Road, Hebbal, Bangalore 560024, Karnataka, India.
AstraZeneca (India) · INCare Institute of Medical Sciences · INFortis Escorts Heart Institute · INGuru Gobind Singh Medical College and Hospital · INKokilaben Dhirubhai Ambani Hospital · INMadras Medical Mission · INRuby Hall Clinic · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited available information for treatment of acute coronary syndrome (ACS) with respect to outcomes, therapeutic agents and treatment practices. Our retrospective registry study collected and evaluated varying anti-platelet treatment strategies and outcomes of ACS patients who were admitted to 9 different tertiary care hospitals in India. This study was carried out to provide an insight to anti-platelet treatment patterns and analyze outcomes of ACS patients in India.

methodsAll the relevant data, including anti-platelet treatment strategies, outcomes and patient treatment compliance were collected from 500 ACS (defined as STEMI, NSTEMI and unstable angina [UA]) cases from January 2007 to December 2009. These ACS cases were randomly collected from the hospital records and included in the analysis. The patient follow up data was acquired either from the hospital records or via telephonic contact for a period of one year following the event.

resultsOut of 500 ACS patients, 59.8% had UA/NSTEMI and 40.2% had STEMI. On hospital admission, aspirin, clopidogrel, statins, beta-blockers and angiotensin converting enzyme inhibitors (ACE-Is) were used by 83%, 83%, 68%, 43.2% and 31.6% patients, respectively. On discharge, aspirin, clopidogrel, statins and beta-blockers were used by 90.2%, 88%, 80.6%, and 59% patients, respectively. The average patient compliance to statins, clopidogrel and aspirin was recorded as 74.28%, 69.7% and 68.66%, respectively during discharge and follow-up visits. Greater than 50% of ACS patients after discharge were lost to follow-up and as a result there was significant drop in the number of clinical events reported.

conclusionThis pilot study conducted in tertiary care centers in India showed that patients with ACS were more often diagnosed with UA/NSTEMI as compared to STEMI and reported maximum compliance to statins, clopidogrel and aspirin after discharge over 1 year follow-up. More ACS patients were lost to follow up that resulted in low reporting of clinical outcomes, following discharge upto 1 year.

Indexed as

RegistriesAcute Coronary SyndromeAgedFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedPilot ProjectsPlatelet Aggregation InhibitorsRetrospective StudiesSurvival RateTreatment OutcomePlatelet Aggregation InhibitorsAcute coronary syndromeNon-ST elevation myocardial infarctionST-elevation myocardial infarctionUnstable angina

Identifiers

PMID24973840
PMCPMC4121748
OpenAlexW2054334823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.