Evidence map›Paper›PMID 24973795›Full record

ArticleThe Journal of pediatrics2014

Variation in resource utilization for the management of uncomplicated community-acquired pneumonia across community and children's hospitals.

JoAnna K Leyenaar, Tara Lagu, Meng-Shiou Shieh, Penelope S Pekow, Peter K Lindenauer

Abstract read
In one paragraph

Article in The Journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Factors associated with antibiotic prescription among patients with respiratory illness in Thailand: The potential impact of rapid influenza diagnostic testing in antimicrobial stewardship.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
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  16. Recent Developments in Pediatric Community-Acquired Pneumonia.Current infectious disease reports · 2016
    Article
  17. Article
  18. Review
  19. Implementation and Impact of an Antimicrobial Stewardship Program at a Non-freestanding Children's Hospital.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

JoAnna K LeyenaarDivision of Pediatric Hospital Medicine, Department of Pediatrics, Tufts University School of Medicine, Boston, MA. Electronic address: jleyenaar@post.harvard.edu.
Tara LaguCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA; Division of General Internal Medicine, Baystate Medical Center, Springfield, MA; Department of Medicine, Tufts University School of Medicine, Boston, MA.
Meng-Shiou ShiehCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA.
Penelope S PekowCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA; Department of Public Health, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA.
Peter K LindenauerCenter for Quality of Care Research, Baystate Medical Center, Springfield, MA; Division of General Internal Medicine, Baystate Medical Center, Springfield, MA; Department of Medicine, Tufts University School of Medicine, Boston, MA.

Funding

TUFTS CLINICAL AND TRANSLATION SCIENCE INSTITUTE (UL1): BPCAUL1RR025752 · NCRR · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2008 to 2011
$17.6M
Tufts CTSI Career Development Program in Comparative Effectiveness ResearchKM1CA156726 · NCI · TUFTS UNIVERSITY BOSTON · PI KENT, DAVID M, SELKER, HARRY P. · 2010 to 2010
$2.5M
Defining Optimal Clinical Strategies for Critically Ill Heart Failure PatientsK01HL114745 · NHLBI · BAYSTATE MEDICAL CENTER, INC. · PI LAGU, TARA C · 2013 to 2017
$721k
NCI NIH HHS KM1CA156726NCRR NIH HHS UL1 RR025752NCRR NIH HHS UL1RR025752NHLBI NIH HHS K01 HL114745NHLBI NIH HHS K01HL114745
6 · The paper itself

Abstract

objectiveTo describe patterns of diagnostic testing and antibiotic management of uncomplicated pneumonia in general community hospitals and children's hospitals within hospitals and to determine the association between diagnostic testing and length of hospital stay. STUDY

designWe conducted a retrospective cohort study of children 1-17 years of age hospitalized with the diagnosis of pneumonia from 2007 to 2010 to hospitals contributing data to Perspective Database Warehouse, assessing patterns of diagnostic testing and antibiotic management. We constructed logistic regression models of log-transformed length of stay (LOS) and grouped treatment models to ascertain whether performance of blood cultures and viral respiratory testing were associated with LOS.

resultsA total of 17 299 pneumonia cases occurred at 125 hospitals, with considerable variability in pneumonia management. Only 40 (0.2%) received ampicillin/penicillin G alone or in combination with other antibiotics, and 1318 (7.4%) received macrolide monotherapy as initial antibiotic management. Performance of blood culture and testing for respiratory viruses was associated with a statistically significant longer LOS, but these differences did not persist in grouped treatment models.

conclusionsWe observed greater rates of diagnostic testing in this cohort of structurally diverse hospitals than previously reported at freestanding children's hospitals, with extremely low rates of narrow-spectrum antibiotic use. Tailored antibiotic stewardship initiatives at these hospitals are needed to achieve adherence to national guideline recommendations.

Indexed as

AdolescentAnti-Bacterial AgentsChildChild, PreschoolCohort StudiesCommunity-Acquired InfectionsFemaleHealth ResourcesHospitals, PediatricHumansInfantLength of StayMalePneumonia, BacterialResidence CharacteristicsRetrospective StudiesAnti-Bacterial Agents

Identifiers

PMID24973795
PMCPMC4158451

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.