ArticleResearch in developmental disabilities2014
Characterizing associations and dissociations between anxiety, social, and cognitive phenotypes of Williams syndrome.
Article in Research in developmental disabilities, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Anxiety Disorders in Williams Syndrome Contrasted with Intellectual Disability and the General Population: A Systematic Review and Meta-Analysis.Journal of autism and developmental disorders · 2017Pooled it
- Behaviour and Psychopathology in Preschool Children with William Syndrome and the Effects of Age, Sex and Cognition.Journal of autism and developmental disorders · 2026Article
- Anxiety in Young Children with Williams Syndrome: A Longitudinal Study.Children (Basel, Switzerland) · 2025Article
- News insights into social cognition in Williams syndrome from a comprehensive assessment and a virtual reality task.Scientific reports · 2024Article
- A cross-comparison of cognitive ability across 8 genomic disorders.Current opinion in genetics & development · 2021Review
- Brief Report: The Impact of Sensory Hypersensitivity and Intolerance of Uncertainty on Anxiety in Williams Syndrome.Journal of autism and developmental disorders · 2018Article
- Anxiety in Williams Syndrome: The Role of Social Behaviour, Executive Functions and Change Over Time.Journal of autism and developmental disorders · 2018Article
- The 7q11.23 Microduplication Syndrome: A Clinical Report with Review of Literature.Journal of pediatric genetics · 2016Review
- Structural integrity of the limbic-prefrontal connection: Neuropathological correlates of anxiety in Williams syndrome.Social neuroscience · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Williams syndrome (WS) is a neurogenetic disorder known for its "hypersocial" phenotype and a complex profile of anxieties. The anxieties are poorly understood specifically in relation to the social-emotional and cognitive profiles. To address this gap, we employed a Wechsler intelligence test, the Brief Symptom Inventory, Beck Anxiety Inventory, and Salk Institute Sociability Questionnaire, to (1) examine how anxiety symptoms distinguish individuals with WS from typically developing (TD) individuals; and (2) assess the associations between three key phenotypic features of WS: intellectual impairment, social-emotional functioning, and anxiety. The results highlighted intensified neurophysiological symptoms and subjective experiences of anxiety in WS. Moreover, whereas higher cognitive ability was positively associated with anxiety in WS, the opposite pattern characterized the TD individuals. This study provides novel insight into how the three core phenotypic features associate/dissociate in WS, specifically in terms of the contribution of cognitive and emotional functioning to anxiety symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.