Evidence map›Paper›PMID 24972923›Full record

ArticleSurgical endoscopy2014

Transanal versus traditional laparoscopic total mesorectal excision for rectal carcinoma.

Simone Velthuis, Dorothee H Nieuwenhuis, T Emiel G Ruijter, Miguel A Cuesta, H Jaap Bonjer, Colin Sietses

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04949672 (Pathology Assessment of Mesorectal Fascia and Specimen Quality After TME by Laparoscopic, Open, TransAnal and Robotic Approaches), which is not on this map. Cited by 73 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 12 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04949672 completednot on this mapstarted 2017, after this paper: background citation

Pathology Assessment of Mesorectal Fascia and Specimen Quality After TME by Laparoscopic, Open, TransAnal and Robotic Approaches (LOTARTME)

Typeobservational_patient_registrySponsorSan Giovanni Addolorata HospitalRan2017 to 2021Enrolled153ConditionsRectal Cancer, Surgery
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 12 syntheses or guidelines pooled it, 195 citations in OpenAlex.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Simone VelthuisDepartment of Surgery, Gelderse Vallei Hospital, 6716 RP, Ede, The Netherlands, velthuissimone@gmail.com.
Dorothee H Nieuwenhuis
T Emiel G Ruijter
Miguel A Cuesta
H Jaap Bonjer
Colin Sietses
Vrije Universiteit Amsterdam · NLZiekenhuis Gelderse Vallei · NLRijnstate Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter total mesorectal excision (TME) surgery, patients with an incomplete mesorectum have an increased risk of local and overall recurrence. With the introduction of laparoscopic TME, an improved quality of the specimen was expected. However, the quality-related results were comparable to the results after traditional open surgery. Transanal TME is a new technique in which the rectum is mobilised by using a single-port and endoscopic instruments through the so called 'down to up' procedure. This new technique potentially leads to an improved specimen quality. This study was designed to investigate the pathological quality of specimens after transanal (TME) and to compare these with specimens after traditional laparoscopic TME.

methodsThis matched case control study compared the specimens of a cohort of consecutive patients who underwent transanal TME with the specimens after traditional laparoscopic TME. The pathological quality of the mesorectum was determined by the definitions of Quirke as 'complete', 'nearly complete', or 'incomplete'.

resultsFrom June 2012 until July 2013, 25 consecutive patients underwent transanal TME because of a rectum carcinoma. Within the transanal TME group, 96% of the specimens had a complete mesorectum, while in the traditional laparoscopic group, 72% was deemed complete (p < 0.05). Other pathological characteristics, such as the circumferential resection margin, were comparable between the two groups.

conclusionsTransanal TME appears associated with a significant higher rate of completeness of the mesorectum. Further studies are necessary to evaluate this novel technique.

Indexed as

AdultAgedAnal CanalColectomyFemaleHumansLaparoscopyMaleMesocolonNatural Orifice Endoscopic SurgeryRectal NeoplasmsRectumRetrospective StudiesTreatment OutcomeYoung Adult

Identifiers

PMID24972923
OpenAlexW2147959959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.