ArticleIntensive care medicine2014
Trends in admission prevalence, illness severity and survival of haematological patients treated in Dutch intensive care units.
Article in Intensive care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wardsTurkish journal of medical sciences · 2021Trial
- [The value of sequential organ failure assessment and its dynamic changes in predicting mortality in hematology intensive care unit].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2025Article
- Severe bleeding events among critically ill patients with haematological malignancies.Annals of intensive care · 2024Article
- Neutropenic Sepsis in the Intensive Care Unit: Differences in Clinical Profile and Outcomes According to the Cause of Neutropenia.Open forum infectious diseases · 2024Article
- Phenotypes and Lung Microbiota Signatures of Immunocompromised Patients with Pneumonia-Related Acute Respiratory Distress Syndrome.Journal of inflammation research · 2024Article
- Prevention of ICU-acquired infection with decontamination regimen in immunocompromised patients: a pre/post observational study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023Observational
- [With a tumor diagnosis in the intensive care unit].Innere Medizin (Heidelberg, Germany) · 2023Review
- Outcomes of CAR-T Cell Therapy Recipients Admitted to the ICU: In Search for a Standard of Care-A Brief Overview and Meta-Analysis of Proportions.Journal of clinical medicine · 2023Review
- Relationship between immunosuppression and intensive care unit-acquired colonization and infection related to multidrug-resistant bacteria: a prospective multicenter cohort study.Intensive care medicine · 2023Article
- Outcomes and Prognostic Factors in Critical Patients with Hematologic Malignancies.Journal of clinical medicine · 2023Article
- Lower versus higher oxygenation targets in ICU patients with haematological malignancy - insights from the HOT-ICU trial.BJA open · 2022Article
- Hospital mortality and prognostic factors in critically ill patients with acute kidney injury and cancer undergoing continuous renal replacement therapy.Kidney research and clinical practice · 2022Article
- A Comprehensive Analysis of 5-Year Outcomes in Patients with Cancer Admitted to Intensive Care Units.Tuberculosis and respiratory diseases · 2022Article
- Critical illness in patients with hematologic malignancy: a population-based cohort study.Intensive care medicine · 2021Article
- Epidemiology, Clinical Characteristics, and Prognostic Factors in Critically Ill Patients with Hematolymphoid Malignancy.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- Acute respiratory failure in immunocompromised patients: outcome and clinical features according to neutropenia status.Annals of intensive care · 2020Article
- Early cost-utility analysis of tissue-engineered heart valves compared to bioprostheses in the aortic position in elderly patients.The European journal of health economics : HEPAC : health economics in prevention and care · 2020Article
- One-year mortality among non-surgical patients with hematological malignancies admitted to the intensive care unit: a Danish nationwide population-based cohort study.Intensive care medicine · 2020Article
- Outcomes for older adults with acute myeloid leukemia after an intensive care unit admission.Cancer · 2019Article
- Factors Associated With Clinical Deterioration Among Patients Hospitalized on the Wards at a Tertiary Cancer Hospital.Journal of oncology practice · 2019Article
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Abstract
purposeTo explore trends over time in admission prevalence and (risk-adjusted) mortality of critically ill haematological patients and compare these trends to those of several subgroups of patients admitted to the medical intensive care unit (medical ICU patients).
methodsA total of 1,741 haematological and 60,954 non-haematological patients admitted to the medical ICU were analysed. Trends over time and differences between two subgroups of haematological medical ICU patients and four subgroups of non-haematological medical ICU patients were assessed, as well as the influence of leukocytopenia.
resultsThe proportion of haematological patients among all medical ICU patients increased over time [odds ratio (OR) 1.06; 95 % confidence interval (CI) 1.03-1.10 per year; p < 0.001]. Risk-adjusted mortality was significantly higher for haematological patients admitted to the ICU with white blood cell (WBC) counts of <1.0 × 10(9)/L (47 %; 95 % CI 41-54 %) and ≥1.0 × 10(9)/L (45 %; 95 % CI 42-49 %), respectively, than for patients admitted with chronic heart failure (27 %; 95 % CI 26-28 %) and with chronic liver cirrhosis (38 %; 95 % CI 35-42 %), but was not significantly different from patients admitted with solid tumours (40 %; 95 % CI 36-45 %). Over the years, the risk-adjusted hospital mortality rate significantly decreased in both the haematological and non-haematological group with an OR of 0.93 (95 % CI 0.92-0.95) per year. After correction for case-mix using the APACHE-II score (with WBC omitted), a WBC <1.0 × 10(9)/L was not a predictor of mortality in haematological patients (OR 0.86; 95 % CI 0.46-1.64; p = 0.65). We found no case-volume effect on mortality for haematological ICU patients.
conclusionsAn increasing number of haematological patients are being admitted to Dutch ICUs. While mortality is significantly higher in this group of medical ICU patients than in subgroups of non-haematological ones, the former show a similar decrease in raw and risk-adjusted mortality rate over time, while leukocytopenia is not a predictor of mortality. These results suggest that haematological ICU patients have benefitted from improved intensive care support during the last decade.
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