Evidence map›Paper›PMID 24972714›Full record

ArticlePlant physiology2014

Genetic Determinants for Enzymatic Digestion of Lignocellulosic Biomass Are Independent of Those for Lignin Abundance in a Maize Recombinant Inbred Population.

Bryan W Penning, Robert W Sykes, Nicholas C Babcock, Christopher K Dugard, Michael A Held, John F Klimek, Jacob T Shreve, Matthew Fowler, Angela Ziebell, Mark F Davis and 8 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
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  7. Redesigning plant cell walls for the biomass-based bioeconomy.The Journal of biological chemistry · 2020
    Review
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  18. Carbohydrate microarrays and their use for the identification of molecular markers for plant cell wall composition.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Bryan W PenningDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Robert W SykesDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Nicholas C BabcockDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Christopher K DugardDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Michael A HeldDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
John F KlimekDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Jacob T ShreveDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Matthew FowlerDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Angela ZiebellDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Mark F DavisDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Stephen R DeckerDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Geoffrey B TurnerDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Nathan S MosierDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Nathan M SpringerDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Jyothi ThimmapuramDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Clifford F WeilDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Maureen C McCannDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.).
Nicholas C CarpitaDepartments of Biological Sciences (B.W.P., M.C.M., N.C.C.), Botany and Plant Pathology (C.K.D., M.A.H., J.F.K., N.C.C.), and Agronomy (N.C.B., C.F.W.), Laboratory of Renewable Resources Engineering and Agricultural and Biological Engineering (N.S.M.), and Bioinformatics Core (J.T.S., J.T.), Purdue University, West Lafayette, Indiana 47907;National Bioenergy Center, National Renewable Energy Laboratory, Golden, Colorado 80401 (R.W.S., M.F., A.Z., M.F.D., S.R.D., G.B.T.); andDepartment of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108 (N.M.S.) carpita@purdue.edu.ORCID http://orcid.org/0000-0003-0770-314X
Purdue University West Lafayette · USNational Laboratory of the Rockies · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biotechnological approaches to reduce or modify lignin in biomass crops are predicated on the assumption that it is the principal determinant of the recalcitrance of biomass to enzymatic digestion for biofuels production. We defined quantitative trait loci (QTL) in the Intermated B73 × Mo17 recombinant inbred maize (Zea mays) population using pyrolysis molecular-beam mass spectrometry to establish stem lignin content and an enzymatic hydrolysis assay to measure glucose and xylose yield. Among five multiyear QTL for lignin abundance, two for 4-vinylphenol abundance, and four for glucose and/or xylose yield, not a single QTL for aromatic abundance and sugar yield was shared. A genome-wide association study for lignin abundance and sugar yield of the 282-member maize association panel provided candidate genes in the 11 QTL of the B73 and Mo17 parents but showed that many other alleles impacting these traits exist among this broader pool of maize genetic diversity. B73 and Mo17 genotypes exhibited large differences in gene expression in developing stem tissues independent of allelic variation. Combining these complementary genetic approaches provides a narrowed list of candidate genes. A cluster of SCARECROW-LIKE9 and SCARECROW-LIKE14 transcription factor genes provides exceptionally strong candidate genes emerging from the genome-wide association study. In addition to these and genes associated with cell wall metabolism, candidates include several other transcription factors associated with vascularization and fiber formation and components of cellular signaling pathways. These results provide new insights and strategies beyond the modification of lignin to enhance yields of biofuels from genetically modified biomass.

Identifiers

PMID24972714
PMCPMC4119032
OpenAlexW2000659606

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