ArticleBMC plant biology2014
Ragweed (Ambrosia artemisiifolia) pollen allergenicity: SuperSAGE transcriptomic analysis upon elevated CO2 and drought stress.
Article in BMC plant biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 109 citations in OpenAlex.
- Elevated COAllergy · 2026Article
- Climate Change, Air Quality, and Pollen Allergies-State of the Art and Recommendations for Research and Public Health.Allergy · 2026Review
- Environmental drivers of the allergenic load caused by Ambrosia artemisiifolia pollen and its major allergen Amb a 1 in the atmosphere.International journal of biometeorology · 2025Article
- Review
- Self-management and information needs of adults with seasonal allergic rhinitis in the Netherlands: A focus group study.Journal of health psychology · 2025Article
- Elevated atmospheric COScientific reports · 2024Article
- Non-Specific Lipid Transfer Protein Amb a 6 Is a Source-Specific Important Allergenic Molecule in Ragweed Pollen.International journal of molecular sciences · 2024Article
- Climate change, airborne allergens, and three translational mitigation approaches.EBioMedicine · 2023Review
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- Epithelial barrier hypothesis: Effect of the external exposome on the microbiome and epithelial barriers in allergic disease.Allergy · 2022Review
- Heat wave event facilitates defensive responses in invasive C3 plantFrontiers in plant science · 2022Article
- Allergo Journal : interdisziplinare Zeitschrift fur Allergologie und Umweltmedizin : Organ der Deutschen Gesellschaft fur Allergie- und Immunitatsforschung · 2022Review
- Climate change and allergies.Allergo journal international · 2022Review
- Plant Stress Scenarios Differentially Affect Expression and IgE Reactivity of Grass Group-1 Allergen (β-Expansin) in Maize and Rice Pollen.Frontiers in allergy · 2022Article
- Autopolyploidization affects transcript patterns and gene targeting frequencies in Physcomitrella.Plant cell reports · 2022Article
- Article
- Influence of the environment on ragweed pollen and their sensitizing capacity in a mouse model of allergic lung inflammation.Frontiers in allergy · 2022Article
- Impact of elevated air temperature and drought on pollen characteristics of major agricultural grass species.PloS one · 2021Article
- Advances and novel developments in environmental influences on the development of atopic diseases.Allergy · 2020Review
- The Clinical Utility of Pollen Counts.Clinical reviews in allergy & immunology · 2019Review
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPollen of common ragweed (Ambrosia artemisiifolia) is a main cause of allergic diseases in Northern America. The weed has recently become spreading as a neophyte in Europe, while climate change may also affect the growth of the plant and additionally may also influence pollen allergenicity. To gain better insight in the molecular mechanisms in the development of ragweed pollen and its allergenic proteins under global change scenarios, we generated SuperSAGE libraries to identify differentially expressed transcripts.
resultsRagweed plants were grown in a greenhouse under 380 ppm CO2 and under elevated level of CO2 (700 ppm). In addition, drought experiments under both CO2 concentrations were performed. The pollen viability was not altered under elevated CO2, whereas drought stress decreased its viability. Increased levels of individual flavonoid metabolites were found under elevated CO2 and/or drought. Total RNA was isolated from ragweed pollen, exposed to the four mentioned scenarios and four SuperSAGE libraries were constructed. The library dataset included 236,942 unique sequences, showing overlapping as well as clear differently expressed sequence tags (ESTs). The analysis targeted ESTs known in Ambrosia, as well as in pollen of other plants. Among the identified ESTs, those encoding allergenic ragweed proteins (Amb a) increased under elevated CO2 and drought stress. In addition, ESTs encoding allergenic proteins in other plants were also identified.
conclusionsThe analysis of changes in the transcriptome of ragweed pollen upon CO2 and drought stress using SuperSAGE indicates that under global change scenarios the pollen transcriptome was altered, and impacts the allergenic potential of ragweed pollen.
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