ArticleEvidence-based dentistry2014
Are children and adolescents with cystic fibrosis at lower risk of caries?
Article in Evidence-based dentistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
data sourcesThe Medline, Embase and Web of Science databases were searched. STUDY SELECTION: Human clinical trials, evaluation studies and systematic reviews related to dental caries prevalence in children and adolescents with CF under age 18 years were included. DATA EXTRACTION AND SYNTHESIS: Standard date items were extracted and risk of bias was assessed using adapted criteria from the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement. A qualitative synthesis was conducted.
resultsFifteen studies met the inclusion criteria, 12 studies were considered as being at high risk of bias and three as medium risk. Ten studies concluded that children with CF had significantly lower caries prevalence than control children, while three studies reported that children with CF had higher caries prevalence, and two studies found no difference by CF status. All of the studies had limitations that may bias the results.
conclusionsWhile children with CF may be at lower risk for dental caries, adolescents with CF may not be at lower caries than those without CF. Additional research is needed to evaluate a potentially flawed paradigm regarding caries risk in children and adolescents with CF.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.