Evidence map›Paper›PMID 24971349›Full record

ReviewBioMed research international2014

CXC and CC chemokines as angiogenic modulators in nonhaematological tumors.

Matteo Santoni, Sergio Bracarda, Massimo Nabissi, Francesco Massari, Alessandro Conti, Emilio Bria, Giampaolo Tortora, Giorgio Santoni, Stefano Cascinu

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Matteo SantoniClinica di Oncologia Medica, AOU "Ospedali Riuniti ," Università Politecnica delle Marche, Via Conca, 60020 Ancona, Italy.ORCID 0000-0001-7340-6173
Sergio BracardaUOC Medical Oncology, Department of Oncology, AUSL8, 52100 Arezzo, Italy.
Massimo NabissiSchool of Pharmacy, Section of Experimental Medicine, University of Camerino, 62032 Camerino, Italy.
Francesco MassariMedical Oncology, Azienda Ospedaliera Universitaria Integrata, University of Verona, Piazzale L.A. Scuro 10, 37124 Verona, Italy.
Alessandro ContiDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Clinica di Urologia, AOU Ospedali Riuniti, Università Politecnica delle Marche, Via Conca 71, 60126 Ancona, Italy.ORCID 0000-0002-7322-9880
Emilio BriaMedical Oncology, Azienda Ospedaliera Universitaria Integrata, University of Verona, Piazzale L.A. Scuro 10, 37124 Verona, Italy.
Giampaolo TortoraMedical Oncology, Azienda Ospedaliera Universitaria Integrata, University of Verona, Piazzale L.A. Scuro 10, 37124 Verona, Italy.
Giorgio SantoniSchool of Pharmacy, Section of Experimental Medicine, University of Camerino, 62032 Camerino, Italy.
Stefano CascinuClinica di Oncologia Medica, AOU "Ospedali Riuniti ," Università Politecnica delle Marche, Via Conca, 60020 Ancona, Italy.
Marche Polytechnic University · ITUniversity of Verona · ITUniversità di Camerino · ITAzienda Usl 8 Arezzo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokines are a superfamily of structurally homologous heparin-binding proteins that includes potent inducers and inhibitors of angiogenesis. The imbalance between angiogenic and angiostatic chemokine activities can lead to abnormalities, such as chronic inflammation, dysplastic transformation, and even tumor development and spreading. In this review, we summarize the current literature regarding the role of chemokines as modulators of tumor angiogenesis and their potential role as therapeutic targets in patients with nonhaematological tumors.

Indexed as

AnimalsCarcinogenesisChemokines, CCChemokines, CXCHumansNeoplasmsNeovascularization, PathologicReceptors, ChemokineChemokines, CCChemokines, CXCReceptors, Chemokine

Identifiers

PMID24971349
PMCPMC4058128
OpenAlexW2035689051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.