Evidence map›Paper›PMID 24971201›Full record

ReviewAnnals of medical and health sciences research2014

Papaya extract to treat dengue: a novel therapeutic option?

N Sarala, Ss Paknikar

Abstract readReview
In one paragraph

Review in Annals of medical and health sciences research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Papaya Leaf Extracts as Potential Dengue Treatment: An In-Silico Study.International journal of molecular sciences · 2022
    Article
  4. Styrylpyrone Derivative (SPD) Extracted fromMolecules (Basel, Switzerland) · 2022
    Article
  5. Review
  6. Review
  7. Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  8. Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  9. Therapeutic application of Carica papaya leaf extract in the management of human diseases.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2020
    Review
  10. Effect OfIntegrative medicine (Encinitas, Calif.) · 2019
    Review
  11. Article
  12. Efficacy and safety ofInternational journal of applied & basic medical research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

N SaralaDepartment of Pharmacology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Tamaka, Kolar, Karnataka, India.
Ss PaknikarConsultant Medical Writer and Editor, Bengaluru, Karnataka, India.
Sri Devaraj Urs Academy of Higher Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue is a viral disease that today affects a vast number of people in over 125 countries and is responsible for a sizable number of deaths. In the absence of an effective antiviral drug to treat the disease, various treatments are being investigated. Studies have indicated that the juice of the leaves of the Carica papaya plant from the family Caricaceae could help to increase the platelet levels in these patients. This review describes some of the published studies on this topic. The search was done independently by the two authors using PubMed, Google and the library database and included relevant articles of the last 10 years. A total of 7 studies were included in this review, which were one animal study, one case report, three case series and two randomized controlled trials. Although many of the studies and case reports published in literature lack adequate information, some of the studies do raise the possibility that this treatment could be an important option in the future. Further large-scale studies could establish the usefulness or ineffectiveness of this natural product in the treatment of dengue.

Indexed as

Carica papaya leavesDengueDengue treatment

Identifiers

PMID24971201
PMCPMC4071726
OpenAlexW2047068400

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.